Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | PREP | P48147 | 1/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | FADS1 | O60427 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 6/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22209897 | 0.81 | DPP4 (0.44) | DPP4PREPDPP8DPP9DPP7 | |
| SCHEMBL5219506 | 0.78 | SSTR2 (0.44) | DPP4PREPDPP8DPP9DPP7 | |
| SCHEMBL4894756 | 0.78 | DPP4 (0.45) | DPP4PREPDPP8DPP9DPP7 | |
| SCHEMBL12483657 | 0.77 | FADS1 (0.45) | DPP4PREPDPP8DPP9DPP7 | |
| SCHEMBL22919251 | 0.75 | HRH3 (0.49) | DPP4PREPDPP8DPP9DPP7 | |
| SCHEMBL4895815 | 0.75 | HRH3 (0.49) | DPP4PREPDPP8DPP9DPP7 | |
| SCHEMBL5222222 | 0.73 | BPTF (0.59) | DPP4PREPDPP8DPP9DPP7 | |
| SCHEMBL18825904 | 0.72 | DRD2 (0.58) | GRM5CHRM4CHRM2KDM4ETP53 | |
| SCHEMBL18825950 | 0.72 | FADS1 (0.41) | DPP4PREPDPP8DPP9DPP7 | |
| Hydrochloric Acid SCHEMBL7236978 | 0.71 | DRD2 (0.57) | GRM5CHRM4CHRM2KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080300251-A1 | Derivatives of 3-Azabicyclo[3.1.0] Hexane as Dipeptidyl Peptidase-IV Inhibitors | RANBAXY LABORATORIES LIMITED (IN) | 2008-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300251-A1 | Derivatives of 3-Azabicyclo[3.1.0] Hexane as Dipeptidyl Peptidase-IV Inhibitors | DPP4, DPP3, DPP8 | DPP4 1/4885PREP 21/4885DPP8 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.