SCHEMBL4898718

SCHEMBL4898718

O=S(=O)(O)c1cc(S(=O)(=O)O)c2[c]cccc2c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ALDH1A1 P00352 4/20 0.39
CASP6 P55212 4/20 0.39
HSD17B10 Q99714 2/20 0.39
CYP2C9 P11712 2/20 0.39
CYP2C19 P33261 1/20 0.39
NT5E P21589 3/20 0.37
MAPK1 P28482 3/20 0.37
TDP1 Q9NUW8 2/20 0.37
NSD2 O96028 3/20 0.35
DUSP3 P51452 2/20 0.35
PTPN5 P54829 2/20 0.35
PTPN11 Q06124 2/20 0.35
CASP7 P55210 1/20 0.35
SUMO2 P61956 1/20 0.35
SUMO1 P63165 1/20 0.35
SENP7 Q9BQF6 1/20 0.35
SENP2 Q9HC62 1/20 0.35
SNCA P37840 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7584941 0.83 CASP6 (0.44) TSHRSMN1; SMN2ALDH1A1CASP6HSD17B10
SCHEMBL2168174 0.79 TTR (0.39) TSHRSMN1; SMN2ALDH1A1CASP6HSD17B10
SCHEMBL7045255 0.77 CASP6 (0.39) TSHRSMN1; SMN2ALDH1A1CASP6HSD17B10
SCHEMBL6597055 0.77 TSHR (0.41) TSHRSMN1; SMN2ALDH1A1CASP6HSD17B10
SCHEMBL7048985 0.75 HSD17B10 (0.40) TSHRSMN1; SMN2ALDH1A1CASP6HSD17B10
SCHEMBL6631839 0.73 ALDH1A1 (0.37) TSHRSMN1; SMN2ALDH1A1CASP6HSD17B10
SCHEMBL7066887 0.73 NT5E (0.44) ALDH1A1CASP6HSD17B10CYP2C9CYP2C19
SCHEMBL1145407 0.73 ALDH1A1 (0.50) TSHRSMN1; SMN2ALDH1A1CASP6HSD17B10
SCHEMBL8599488 0.73 ALDH1A1 (0.50) TSHRSMN1; SMN2ALDH1A1CASP6HSD17B10
SCHEMBL29421128 0.73 ALDH1A1 (0.50) TSHRSMN1; SMN2ALDH1A1CASP6HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114945636-B Azo compound or salt thereof, polarizing film, polarizing plate, and display device 日本化药株式会社 2024-07-12 CN disclosed
US-20080119643-A1 4,4'-Diazobenzanilide Dyestuffs LENNARTZ MICHAEL 2008-05-22 US disclosed
CN-101040010-A 4,4'-diazobenzanilide dyestuffs CIBA SC HOLDING AG (CH) 2007-09-19 CN disclosed
CN-1276035-C Water-color ink MITSUI CHEMICALS INC (JP) 2006-09-20 CN disclosed
CN-1558934-A Water-color ink 三井化学株式会社 2004-12-29 CN disclosed
US-20040231558-A1 Has a clear hue, high light fastness and high moisture resistance MITSUI CHEMICALS, INC. (JP) 2004-11-25 US disclosed
EP-1441013-A1 WATERCOLOR INK Mitsui Chemicals, Inc. (JP) 2004-07-28 EP disclosed
US-5147770-A Entitled silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1992-09-15 US disclosed
US-4837320-A BRILLIANT, COLORFAST BLUE DYES BAYER AKTIENGESELLSCHAFT (DE) 1989-06-06 US disclosed
US-4214082-A Anthraquinone reactive dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1980-07-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080119643-A1 4,4'-Diazobenzanilide Dyestuffs CYP4B1, TYR, DDT TSHR 3647/4885SMN1; SMN2 4536/4885ALDH1A1 155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.