Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4898777 | 1.00 | ALDH1A1 (0.40) | ALDH1A1KDM4EGAACHRM2CHRM4 | |
| SCHEMBL4902366 | 0.85 | ALDH1A1 (0.56) | ALDH1A1KDM4EGAARAB9AMAPT | |
| SCHEMBL4902361 | 0.85 | ALDH1A1 (0.56) | ALDH1A1KDM4EGAARAB9AMAPT | |
| SCHEMBL4893965 | 0.77 | ALDH1A1 (0.54) | ALDH1A1KDM4EGAARAB9AMAPT | |
| SCHEMBL4893970 | 0.77 | ALDH1A1 (0.54) | ALDH1A1KDM4EGAARAB9AMAPT | |
| SCHEMBL4899573 | 0.75 | ALDH1A1 (0.47) | ALDH1A1KDM4EGAACHRM2CHRM4 | |
| SCHEMBL4899577 | 0.75 | ALDH1A1 (0.47) | ALDH1A1KDM4EGAACHRM2CHRM4 | |
| SCHEMBL9915629 | 0.72 | CHRM2 (0.60) | ALDH1A1KDM4ECHRM2CHRM4CHRM5 | |
| SCHEMBL3045310 | 0.72 | CHRM2 (0.60) | ALDH1A1KDM4ECHRM2CHRM4CHRM5 | |
| SCHEMBL3045309 | 0.72 | CHRM2 (0.60) | ALDH1A1KDM4ECHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853352-B2 | Functionalized polymer and method for making | BRIDGESTONE CORPORATION (JP) | 2014-10-07 | — | — | US | disclosed |
| US-20080154020-A1 | introducing imine compounds into carbanionic (living) polymers, that can interact with particle filler such as carbon black and silica | BRIDGESTONE CORPORATION (JP) | 2008-06-26 | — | — | US | disclosed |