Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | INSR | P06213 | 1/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.39 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4899573 | 1.00 | ALDH1A1 (0.47) | ALDH1A1KMT2AKDM4EGAACHRM2 | |
| SCHEMBL5377395 | 0.91 | ALDH1A1 (0.46) | ALDH1A1KMT2AKDM4EGAACHRM2 | |
| SCHEMBL5377397 | 0.91 | ALDH1A1 (0.46) | ALDH1A1KMT2AKDM4EGAACHRM2 | |
| SCHEMBL4899121 | 0.82 | ALDH1A1 (0.67) | ALDH1A1KMT2AKDM4EGAAMEN1 | |
| SCHEMBL4899125 | 0.82 | ALDH1A1 (0.67) | ALDH1A1KMT2AKDM4EGAAMEN1 | |
| SCHEMBL20163323 | 0.81 | ALDH1A1 (0.57) | ALDH1A1KMT2AKDM4EGAAMEN1 | |
| SCHEMBL18321013 | 0.81 | ALDH1A1 (0.57) | ALDH1A1KMT2AKDM4EGAAMEN1 | |
| SCHEMBL15086509 | 0.80 | ALDH1A1 (0.56) | ALDH1A1KMT2AKDM4EGAAMEN1 | |
| SCHEMBL9915629 | 0.80 | CHRM2 (0.60) | ALDH1A1KMT2AKDM4ECHRM2CHRM4 | |
| SCHEMBL3045309 | 0.80 | CHRM2 (0.60) | ALDH1A1KMT2AKDM4ECHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853352-B2 | Functionalized polymer and method for making | BRIDGESTONE CORPORATION (JP) | 2014-10-07 | — | — | US | disclosed |
| US-20080154020-A1 | introducing imine compounds into carbanionic (living) polymers, that can interact with particle filler such as carbon black and silica | BRIDGESTONE CORPORATION (JP) | 2008-06-26 | — | — | US | disclosed |