Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 10/20 | 0.50 |
| ▸ | MAOA | P21397 | 9/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | KIF11 | P52732 | 2/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4897471 | 0.79 | CYP11B1 (0.56) | CYP11B1CYP11B2PDE3BPDE3ANOTUM | |
| SCHEMBL4890586 | 0.78 | KIF11 (0.58) | CYP11B1CYP11B2PDE3BPDE3ANOTUM | |
| SCHEMBL4891714 | 0.76 | KIF11 (0.49) | CYP11B1CYP11B2PDE3BPDE3ANOTUM | |
| SCHEMBL25904133 | 0.75 | CYP11B1 (0.59) | CYP11B1CYP11B2MAOBMAOAPDE3B | |
| SCHEMBL4596362 | 0.74 | KIF11 (0.61) | CYP11B1CYP11B2MAOBMAOAPDE3B | |
| SCHEMBL25904981 | 0.71 | MAOB (0.78) | CYP11B1CYP11B2MAOBMAOAPDE3B | |
| SCHEMBL4898364 | 0.71 | CYP11B1 (0.52) | CYP11B1CYP11B2MAOBMAOAPDE3B | |
| SCHEMBL1878844 | 0.71 | CYP11B1 (0.66) | CYP11B1CYP11B2MAOBMAOAPDE3B | |
| SCHEMBL4888650 | 0.71 | KIF11 (0.67) | CYP11B1CYP11B2MAOBMAOAPDE3B | |
| SCHEMBL5751107 | 0.71 | MAOB (0.64) | CYP11B1CYP11B2MAOBMAOAPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080176830-A1 | Compounds, Compositions, and Methods | ADAMS NICHOLAS D | 2008-07-24 | — | — | US | claimed |
| US-20080176830-A1 | Compounds, Compositions, and Methods | ADAMS NICHOLAS D | 2008-07-24 | — | — | US | disclosed |
| US-20080176830-A1 | Compounds, Compositions, and Methods | ADAMS NICHOLAS D | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176830-A1 | Compounds, Compositions, and Methods | ALPP, PCNA, MKI67 | CYP11B1 780/4885CYP11B2 1046/4885MAOB 2353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.