SCHEMBL489897

SCHEMBL489897

CCCCCCCCC(=Cc1ccccc1)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.67
LMNA P02545 1/20 0.64
CES2 O00748 2/20 0.54
CES1 P23141 2/20 0.54
ALOX5 P09917 2/20 0.53
PTGES O14684 1/20 0.53
PPARG P37231 1/20 0.53
CYP3A4 P08684 1/20 0.53
CYP2C9 P11712 1/20 0.53
APEX1 P27695 2/20 0.52
RECQL P46063 1/20 0.47
EGFR P00533 1/20 0.47
EPHX2 P34913 1/20 0.46
MEN1 O00255 1/20 0.46
ALDH1A1 P00352 1/20 0.46
MAPT P10636 1/20 0.46
HTT P42858 1/20 0.46
KMT2A Q03164 1/20 0.46
ATM Q13315 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9302259 1.00 TDP1 (0.67) TDP1LMNACES2CES1ALOX5
SCHEMBL5467262 1.00 TDP1 (0.67) TDP1LMNACES2CES1ALOX5
SCHEMBL6437828 1.00 TDP1 (0.67) TDP1LMNACES2CES1ALOX5
SCHEMBL27679125 1.00 TDP1 (0.67) TDP1LMNACES2CES1ALOX5
SCHEMBL3250732 1.00 TDP1 (0.67) TDP1LMNACES2CES1ALOX5
SCHEMBL5467260 1.00 TDP1 (0.67) TDP1LMNACES2CES1ALOX5
SCHEMBL3684325 1.00 TDP1 (0.67) TDP1LMNACES2CES1ALOX5
SCHEMBL17629135 0.98 LMNA (0.66) TDP1LMNACES2CES1ALOX5
SCHEMBL17629136 0.98 LMNA (0.66) TDP1LMNACES2CES1ALOX5
SCHEMBL28271475 0.98 LMNA (0.66) TDP1LMNACES2CES1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078211-A1 A SOLID PARTICLE OF ORGANOSILICON-FUNCTIONAL CO-POLYMER, MANUFACTURING PROCESS THEREOF, AND COSMETICS COMPRISING SAID SOLID PARTICLE DOW TORAY CO LTD (JP) 2026-03-19 US disclosed
EP-4626941-A1 A SOLID PARTICLE OF ORGANOSILICON-FUNCTIONAL CO-POLYMER, MANUFACTURING PROCESSTHEREOF, AND COSMETICS COMPRISING SAID SOLID PARTICLE Dow Toray Co., Ltd. (JP) 2025-10-08 EP disclosed
US-20240225981-A1 Synthesized Molecule of Solketal Esters from Palm Kit Oil and Glycerin for Cosmetic and Agricultural Formulations NUOL GREEN CHEMISTRY LLC 2024-07-11 US disclosed
WO-2024113195-A1 A SOLID PARTICLE OF ORGANOSILICON-FUNCTIONAL CO-POLYMER, MANUFACTURING PROCESSTHEREOF, AND COSMETICS COMPRISING SAID SOLID PARTICLE DOW TORAY CO., LTD. (JP) 2024-06-06 WO disclosed
EP-3257497-B1 ANTIOXIDANT AGENT, ANTIOXIDANT COSMETIC AND UV CARE COSMETIC BASED ON ENZYMATICALLY SYNTHESIZED GLYCOGEN OR AN ALPHA-AMYLASE DIGEST THEREOF EZAKI GLICO CO (JP) 2024-04-24 EP disclosed
WO-2023106267-A1 OIL-IN-WATER ULTRAVIOLET-PROTECTIVE COSMETIC 岩瀬コスファ株式会社 2023-06-15 WO disclosed
WO-2022255352-A1 DERMATOLOGICAL TOPICAL AGENT 花王株式会社 2022-12-08 WO disclosed
US-20220339083-A1 EMULSION COMPOSITION, COSMETIC COMPOSITION, AND METHOD FOR PREPARING EMULSION COMPOSITION DAIO PAPER CORPORATION (JP) 2022-10-27 US disclosed
EP-4039246-A1 EMULSION COMPOSITION, COSMETIC COMPOSITION, AND METHOD FOR PRODUCING EMULSION COMPOSITION Daio Paper Corporation (JP) 2022-08-10 EP disclosed
WO-2022092284-A1 COMPOSITION CONTAINING LIPID PEPTIDE AND SUCROSE ESTER 日産化学株式会社 2022-05-05 WO disclosed
EP-1002515-A1 SKIN COMPOSITIONS FOR EXTERNAL USE SHISEIDO COMPANY LIMITED (JP) 2000-05-24 EP disclosed
EP-0953336-A1 FINE ULTRAVIOLET SCREENING PARTICLES, PROCESS FOR PREPARING THE SAME, AND COSMETIC PREPARATION Kao Corporation (JP) 1999-11-03 EP disclosed
US-5853711-A Water-in-oil emulsion cosmetic composition SHISEIDO COMPANY, LTD (JP) 1998-12-29 US disclosed
EP-0882447-A1 SOLUBLE COSMETICS SHISEIDO COMPANY LIMITED (JP) 1998-12-09 EP disclosed
US-5827507-A MATRIX PARTICLES AND DAUGHTER PARTICLES OF DIFFERENT BAND GAP ENERGIES KAO CORPORATION (JP) 1998-10-27 US disclosed
EP-0721484-B1 ULTRAVIOLET SHIELDING COMPOSITE FINE PARTICLES, METHOD FOR PRODUCING THE SAME, AND COSMETICS KAO CORP (JP) 1998-06-17 EP disclosed
EP-0765656-A1 Water-in-oil type emulsion cosmetic composition SHISEIDO COMPANY LIMITED (JP) 1997-04-02 EP disclosed
EP-0721484-A1 ULTRAVIOLET SHIELDING COMPOSITE FINE PARTICLES, METHOD FOR PRODUCING THE SAME, AND COSMETICS Kao Corporation (JP) 1996-07-17 EP disclosed
EP-0702065-A2 Method for preventing settlement of aquatic fouling organisms Nippon Paint Co., Ltd. (JP) 1996-03-20 EP disclosed
WO-1995009895-A1 ULTRAVIOLET SHIELDING COMPOSITE FINE PARTICLES, METHOD FOR PRODUCING THE SAME, AND COSMETICS KAO CORPORATION (JP) 1995-04-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078211-A1 A SOLID PARTICLE OF ORGANOSILICON-FUNCTIONAL CO-POLYMER, MANUFACTURING PROCESS THEREOF, AND COSMETICS COMPRISING SAID SOLID PARTICLE FOXM1, FOXK1, TAF1L TDP1 2174/4885LMNA 1322/4885CES2 3498/4885
US-20240225981-A1 Synthesized Molecule of Solketal Esters from Palm Kit Oil and Glycerin for Cosmetic and Agricultural Formulations DGKK, DGKA, DGKG TDP1 2488/4885LMNA 1800/4885CES2 624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.