Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PGD | P52209 | 1/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3224348 | 0.81 | CYP2C19 (0.58) | CYP2C19PGDLMNATDP1ALDH1A1 | |
| SCHEMBL9856879 | 0.76 | CYP2C19 (0.52) | CYP2C19LMNATDP1ALDH1A1TP53 | |
| SCHEMBL9574851 | 0.76 | CYP2C19 (0.52) | CYP2C19LMNATDP1ALDH1A1TP53 | |
| SCHEMBL8382997 | 0.74 | CYP2C19 (0.61) | CYP2C19TDP1ALDH1A1 | |
| SCHEMBL667280 | 0.72 | PGD (0.50) | CYP2C19SLC22A6SMN1; SMN2PGDGABRR1 | |
| SCHEMBL6803525 | 0.72 | PGD (0.50) | CYP2C19SLC22A6SMN1; SMN2PGDGABRR1 | |
| SCHEMBL6805671 | 0.72 | PGD (0.50) | CYP2C19SLC22A6SMN1; SMN2PGDGABRR1 | |
| SCHEMBL1967208 | 0.72 | SLC22A6 (0.48) | SLC22A6SMN1; SMN2PGDGABRR1LMNA | |
| SCHEMBL21399526 | 0.72 | SLC22A6 (0.48) | SLC22A6SMN1; SMN2PGDGABRR1LMNA | |
| SCHEMBL321641 | 0.72 | SLC22A6 (0.48) | SLC22A6SMN1; SMN2PGDGABRR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080003288-A1 | Responsive microgel and methods related thereto | SUPRATEK PHARMA INC. (CA) | 2008-01-03 | — | — | US | disclosed |
| US-7204997-B2 | Responsive microgel and methods related thereto | SUPRATEK PHARMA INC. (CA) | 2007-04-17 | — | — | US | disclosed |
| EP-1478403-A1 | RESPONSIVE MICROGEL AND METHODS RELATED THERETO | SUPRATEK PHARMA, INC. (CA) | 2004-11-24 | — | — | EP | disclosed |
| US-20030152623-A1 | Responsive microgel and methods related thereto | SUPRATEK PHARMA INC. (CA) | 2003-08-14 | — | — | US | disclosed |
| WO-2003063909-A1 | RESPONSIVE MICROGEL AND METHODS RELATED THERETO | SUPRATEK PHARMA INC. (US) | 2003-08-07 | — | — | WO | disclosed |
| EP-1196436-A2 | PEPTIDE BORONIC ACID INHIBITORS OF HEPATITIS C VIRUS PROTEASE | Bristol-Myers Squibb Pharma Company (US) | 2002-04-17 | — | — | EP | disclosed |
| EP-0709373-B1 | PYRROLIDINE DERIVATIVE | ZAIDAN HOJIN BISEIBUTSU (JP) | 2001-10-17 | — | — | EP | disclosed |
| WO-2001002424-A2 | PEPTIDE BORONIC ACID INHIBITORS OF HEPATITIS C VIRUS PROTEASE | DU PONT PHARMACEUTICALS COMPANY (US) | 2001-01-11 | — | — | WO | disclosed |
| EP-0910351-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. Searle & Co. (US) | 1999-04-28 | — | — | EP | disclosed |
| EP-0907666-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. Searle & Co. (US) | 1999-04-14 | — | — | EP | disclosed |
| EP-0078498-B1 | METHOD FOR PROTECTING AMINO GROUP AND RESTORING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 1986-01-15 | — | — | EP | disclosed |
| EP-0167097-A1 | Process for preparing chloroolefins | BASF Aktiengesellschaft (DE) | 1986-01-08 | — | — | EP | disclosed |
| US-4562197-A | CATTLE, POULTRY | PFIZER INC. (US) | 1985-12-31 | — | — | US | disclosed |
| EP-0144230-A2 | Growth promotants for animals | Pfizer Limited (GB) | 1985-06-12 | — | — | EP | disclosed |
| EP-0077393-A1 | NOVEL METHOD OF ADMINISTERING NARCOTIC ANTAGONISTS AND ANALGESICS AND NOVEL DOSAGE FORMS CONTAINING SAME | The University of Kentucky Research Foundation (US) | 1983-04-27 | — | — | EP | disclosed |
| WO-1982003768-A1 | NOVEL METHOD OF ADMINISTERING NARCOTIC ANTAGONISTS AND ANALGESICS AND NOVEL DOSAGE FORMS CONTAINING SAME | UNIV KENTUCKY (US) | 1982-11-11 | — | — | WO | disclosed |
| US-4234517-A | 2-(2',2'-Dihalovinyl)-cyclobutanones and 2-(2',2',2'-trihaloethyl)-cyclobutanones | CIBA-GEIGY CORPORATION (US) | 1980-11-18 | — | — | US | disclosed |
| US-4206283-A | PROCIDINS PRODUCED BY STREPTOMYCES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-06-03 | — | — | US | disclosed |
| US-4092356-A | 11,12-Secoprostaglandins | MERCK & CO., INC. (US) | 1978-05-30 | — | — | US | disclosed |
| US-4066692-A | 11,12-SECOPROSTAGLANDINS | MERCK & CO., INC. (US) | 1978-01-03 | — | — | US | disclosed |