Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.67 |
| ▸ | GAA | P10253 | 8/20 | 0.67 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.59 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 11/20 | 0.54 |
| ▸ | GFER | P55789 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CASP1 | P29466 | 3/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | HBB | P68871 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | ESRRG | P62508 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4899125 | 1.00 | ALDH1A1 (0.67) | ALDH1A1KDM4EGAAALDH3A1ALDH1A3 | |
| SCHEMBL15172948 | 0.91 | ALDH1A1 (0.61) | ALDH1A1KDM4EGAAALDH3A1ALDH1A3 | |
| SCHEMBL15172910 | 0.91 | ALDH1A1 (0.61) | ALDH1A1KDM4EGAAALDH3A1ALDH1A3 | |
| SCHEMBL15172947 | 0.91 | ALDH1A1 (0.61) | ALDH1A1KDM4EGAAALDH3A1ALDH1A3 | |
| SCHEMBL15172911 | 0.91 | ALDH1A1 (0.61) | ALDH1A1KDM4EGAAALDH3A1ALDH1A3 | |
| SCHEMBL5379791 | 0.89 | ALDH1A1 (0.64) | ALDH1A1KDM4EGAAALDH3A1ALDH1A3 | |
| SCHEMBL5379796 | 0.89 | ALDH1A1 (0.64) | ALDH1A1KDM4EGAAALDH3A1ALDH1A3 | |
| SCHEMBL18321013 | 0.88 | ALDH1A1 (0.57) | ALDH1A1KDM4EGAAALDH3A1ALDH1A3 | |
| SCHEMBL20163323 | 0.88 | ALDH1A1 (0.57) | ALDH1A1KDM4EGAAALDH3A1ALDH1A3 | |
| SCHEMBL15086509 | 0.86 | ALDH1A1 (0.56) | ALDH1A1KDM4EGAAALDH3A1ALDH1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853352-B2 | Functionalized polymer and method for making | BRIDGESTONE CORPORATION (JP) | 2014-10-07 | — | — | US | disclosed |
| US-20080154020-A1 | introducing imine compounds into carbanionic (living) polymers, that can interact with particle filler such as carbon black and silica | BRIDGESTONE CORPORATION (JP) | 2008-06-26 | — | — | US | disclosed |