Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.57 |
| ▸ | GAA | P10253 | 8/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.50 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 12/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | CASP1 | P29466 | 3/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HBB | P68871 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | ESRRG | P62508 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18321013 | 1.00 | ALDH1A1 (0.57) | ALDH1A1KDM4EGAAKMT2AMEN1 | |
| SCHEMBL15086509 | 0.98 | ALDH1A1 (0.56) | ALDH1A1KDM4EGAAKMT2AMEN1 | |
| SCHEMBL15172911 | 0.93 | ALDH1A1 (0.61) | ALDH1A1KDM4EGAAKMT2AMEN1 | |
| SCHEMBL15172948 | 0.93 | ALDH1A1 (0.61) | ALDH1A1KDM4EGAAKMT2AMEN1 | |
| SCHEMBL15172947 | 0.93 | ALDH1A1 (0.61) | ALDH1A1KDM4EGAAKMT2AMEN1 | |
| SCHEMBL15172910 | 0.93 | ALDH1A1 (0.61) | ALDH1A1KDM4EGAAKMT2AMEN1 | |
| SCHEMBL4899121 | 0.88 | ALDH1A1 (0.67) | ALDH1A1KDM4EGAAKMT2AMEN1 | |
| SCHEMBL4899125 | 0.88 | ALDH1A1 (0.67) | ALDH1A1KDM4EGAAKMT2AMEN1 | |
| SCHEMBL9810590 | 0.84 | ALDH1A1 (0.57) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL9810599 | 0.84 | ALDH1A1 (0.57) | ALDH1A1KDM4EKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11059778-B2 | Cannabinoid receptor CB2 ligand 4-(aminomethyl)-N, N-dialkylanilines | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2021-07-13 | — | — | US | disclosed |
| US-20200270205-A1 | NOVEL CANNABINOID RECEPTOR CB2 LIGAND 4-(AMINOMETHYL)-N, N-DIALKYLANILINES | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-08-27 | — | — | US | disclosed |
| US-10696624-B2 | Cannabinoid receptor CB2 ligand 4-(aminomethyl)-N,N-dialkylanilines | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2020-06-30 | — | — | US | disclosed |
| US-20180141902-A1 | NOVEL CANNABINOID RECEPTOR CB2 LIGAND 4-(AMINOMETHYL)-N,N-DIALKYLANILINES | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11059778-B2 | Cannabinoid receptor CB2 ligand 4-(aminomethyl)-N, N-dialkylanilines | CNR2, CNR1, GPR174 | ALDH1A1 4399/4885KDM4E 1011/4885GAA 4834/4885 |
| US-20200270205-A1 | NOVEL CANNABINOID RECEPTOR CB2 LIGAND 4-(AMINOMETHYL)-N, N-DIALKYLANILINES | CNR2, CNR1, GPR174 | ALDH1A1 4373/4885KDM4E 1040/4885GAA 4846/4885 |
| US-20180141902-A1 | NOVEL CANNABINOID RECEPTOR CB2 LIGAND 4-(AMINOMETHYL)-N,N-DIALKYLANILINES | CNR2, CNR1, GPR174 | ALDH1A1 4390/4885KDM4E 840/4885GAA 4837/4885 |
| US-10696624-B2 | Cannabinoid receptor CB2 ligand 4-(aminomethyl)-N,N-dialkylanilines | CNR2, CNR1, GPR174 | ALDH1A1 4399/4885KDM4E 1011/4885GAA 4834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.