Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 11/20 | 0.43 |
| ▸ | HTR1A | P08908 | 7/20 | 0.42 |
| ▸ | HTR2B | P41595 | 7/20 | 0.42 |
| ▸ | HTR5A | P47898 | 6/20 | 0.42 |
| ▸ | HTR2C | P28335 | 4/20 | 0.42 |
| ▸ | HTR6 | P50406 | 4/20 | 0.42 |
| ▸ | HTR1D | P28221 | 5/20 | 0.40 |
| ▸ | HTR1B | P28222 | 5/20 | 0.40 |
| ▸ | HTR2A | P28223 | 5/20 | 0.40 |
| ▸ | HTR1E | P28566 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | TSPO | P30536 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932173 | 0.75 | ALDH1A1 (0.46) | HTR7HTR1AHTR2BHTR5AHTR2C | |
| SCHEMBL5689799 | 0.73 | CA1 (0.44) | HTR7ALDH1A1CA12CA1CA2 | |
| SCHEMBL301996 | 0.71 | CA1 (0.71) | HTR7ALDH1A1HPGDRAB9AHSD17B10 | |
| SCHEMBL29429633 | 0.71 | CA1 (0.71) | HTR7ALDH1A1HPGDRAB9AHSD17B10 | |
| SCHEMBL29788337 | 0.71 | CA1 (0.71) | HTR7ALDH1A1HPGDRAB9AHSD17B10 | |
| SCHEMBL10412382 | 0.70 | HTR7 (0.44) | HTR7HTR1AHTR2BHTR5AHTR2C | |
| SCHEMBL14088330 | 0.69 | CA1 (0.40) | ALDH1A1CA12CA1CA2CA4 | |
| SCHEMBL4439075 | 0.69 | HTR7 (0.40) | HTR7HTR1AHTR2BHTR5AHTR2C | |
| SCHEMBL3643541 | 0.69 | CA1 (0.67) | HTR7ALDH1A1HPGDHSD17B10APP | |
| SCHEMBL29740506 | 0.69 | CA1 (0.67) | HTR7ALDH1A1HPGDRAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404915-B2 | 1) at least one diaryl-substituted diphosphine ligand; 2) a chromium metal precursor; and 3) optionally, one or more activators | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-03-26 | — | — | US | disclosed |
| US-20080058486-A1 | Phosphine Ligand-Metal Compositions, Complexes, and Catalysts For Ethylene Trimerizations | SYMYX TECHNOLOGIES INC. | 2008-03-06 | — | — | US | disclosed |