Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | CA1 | P00915 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.57 |
| ▸ | FBP1 | P09467 | 2/20 | 0.56 |
| ▸ | VCP | P55072 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4900542 | 1.00 | KMT2A (0.66) | KMT2AMEN1CA1CA2AMY1A | |
| SCHEMBL9698864 | 0.92 | CA1 (0.61) | KMT2AMEN1CA1CA2AMY1A | |
| SCHEMBL9698869 | 0.92 | CA1 (0.61) | KMT2AMEN1CA1CA2AMY1A | |
| SCHEMBL9181666 | 0.88 | ALDH1A1 (0.58) | KMT2AMEN1CA1CA2AMY1A | |
| SCHEMBL9181669 | 0.88 | ALDH1A1 (0.58) | KMT2AMEN1CA1CA2AMY1A | |
| SCHEMBL10663163 | 0.88 | ALDH1A1 (0.58) | KMT2AMEN1CA1CA2AMY1A | |
| SCHEMBL9408027 | 0.87 | CA1 (0.56) | KMT2AMEN1CA1CA2AMY1A | |
| SCHEMBL9408024 | 0.87 | CA1 (0.56) | KMT2AMEN1CA1CA2AMY1A | |
| SCHEMBL2909279 | 0.84 | KMT2A (0.56) | KMT2AMEN1CA1CA2AMY1A | |
| SCHEMBL2909281 | 0.84 | KMT2A (0.56) | KMT2AMEN1CA1CA2AMY1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853352-B2 | Functionalized polymer and method for making | BRIDGESTONE CORPORATION (JP) | 2014-10-07 | — | — | US | disclosed |
| US-20080154020-A1 | introducing imine compounds into carbanionic (living) polymers, that can interact with particle filler such as carbon black and silica | BRIDGESTONE CORPORATION (JP) | 2008-06-26 | — | — | US | disclosed |