Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | FBP1 | P09467 | 2/20 | 0.50 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | VCP | P55072 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9408027 | 1.00 | CA1 (0.56) | CA1CA2MEN1KMT2AFBP1 | |
| SCHEMBL9698869 | 0.91 | CA1 (0.61) | CA1CA2MEN1KMT2AFBP1 | |
| SCHEMBL9698864 | 0.91 | CA1 (0.61) | CA1CA2MEN1KMT2AFBP1 | |
| SCHEMBL4900549 | 0.87 | KMT2A (0.66) | CA1CA2MEN1KMT2AFBP1 | |
| SCHEMBL4900542 | 0.87 | KMT2A (0.66) | CA1CA2MEN1KMT2AFBP1 | |
| SCHEMBL9181669 | 0.84 | ALDH1A1 (0.58) | CA1CA2MEN1KMT2AFBP1 | |
| SCHEMBL9181666 | 0.84 | ALDH1A1 (0.58) | CA1CA2MEN1KMT2AFBP1 | |
| SCHEMBL10663163 | 0.84 | ALDH1A1 (0.58) | CA1CA2MEN1KMT2AFBP1 | |
| SCHEMBL9407923 | 0.84 | MEN1 (0.53) | CA1CA2MEN1KMT2AAMY1A | |
| SCHEMBL9407921 | 0.84 | MEN1 (0.53) | CA1CA2MEN1KMT2AAMY1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609032-A1 | Aromatic imine compounds, pharmaceutical composition thereof, useful as protein synthesis inhibitors | NORSK HYDRO A/S (NO) | 1994-08-03 | — | — | EP | claimed |
| EP-0609032-A1 | Aromatic imine compounds, pharmaceutical composition thereof, useful as protein synthesis inhibitors | NORSK HYDRO A/S (NO) | 1994-08-03 | — | — | EP | disclosed |