Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4302766 | 0.94 | KDM4E (0.58) | KDM4ETDP1KMT2AALDH1A1MEN1 | |
| SCHEMBL4822552 | 0.91 | KDM4E (0.63) | KDM4ETDP1KMT2AALDH1A1MEN1 | |
| Formic Acid SCHEMBL4815811 | 0.88 | CCR5 (0.48) | KDM4ETDP1KMT2AALDH1A1MEN1 | |
| SCHEMBL4360309 | 0.85 | KDM4E (0.49) | KDM4ETDP1KMT2AALDH1A1MEN1 | |
| SCHEMBL14181860 | 0.84 | CCR5 (0.53) | KDM4ETDP1KMT2AALDH1A1MEN1 | |
| Formic Acid SCHEMBL4908786 | 0.84 | SPHK2 (0.42) | KDM4ETDP1KMT2AALDH1A1MEN1 | |
| SCHEMBL14027632 | 0.83 | KDM4E (0.49) | KDM4ETDP1KMT2AALDH1A1MEN1 | |
| SCHEMBL4815814 | 0.82 | KMT2A (0.43) | KDM4ETDP1KMT2AALDH1A1MEN1 | |
| SCHEMBL14027305 | 0.82 | CCR5 (0.52) | KDM4ETDP1KMT2AALDH1A1MEN1 | |
| SCHEMBL4366403 | 0.82 | CCR5 (0.52) | KDM4ETDP1KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269217-A1 | Melanocortin-4 receptor binding compounds and methods of use thereof | ORE PHARMACEUTICALS, INC. (US) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269217-A1 | Melanocortin-4 receptor binding compounds and methods of use thereof | MC4R, MC5R, MC3R | KDM4E 1351/4885TDP1 4856/4885KMT2A 1838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.