Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.41 |
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14027306 | 0.96 | SPHK2 (0.44) | SPHK2SPHK1CD274PDCD1LG2KDM4E | |
| SCHEMBL14027308 | 0.96 | SPHK2 (0.44) | SPHK2SPHK1CD274PDCD1LG2KDM4E | |
| SCHEMBL4361737 | 0.96 | SPHK2 (0.44) | SPHK2SPHK1CD274PDCD1LG2KDM4E | |
| SCHEMBL4366788 | 0.93 | SPHK2 (0.42) | SPHK2SPHK1CD274PDCD1LG2KDM4E | |
| SCHEMBL4908791 | 0.89 | FAAH (0.41) | KDM4EALDH1A1CCR5MEN1TSHR | |
| SCHEMBL14027638 | 0.87 | FAAH (0.44) | KDM4EALDH1A1CCR5MEN1TSHR | |
| SCHEMBL4307265 | 0.87 | FAAH (0.44) | KDM4EALDH1A1CCR5MEN1TSHR | |
| SCHEMBL14027317 | 0.87 | FAAH (0.44) | KDM4EALDH1A1CCR5MEN1TSHR | |
| Formic Acid SCHEMBL4901439 | 0.84 | KDM4E (0.52) | KDM4EALDH1A1CCR5MEN1TSHR | |
| SCHEMBL14027328 | 0.82 | KDM4E (0.43) | SPHK2SPHK1CD274PDCD1LG2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269217-A1 | Melanocortin-4 receptor binding compounds and methods of use thereof | ORE PHARMACEUTICALS, INC. (US) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269217-A1 | Melanocortin-4 receptor binding compounds and methods of use thereof | MC4R, MC5R, MC3R | SPHK2 2578/4885SPHK1 3350/4885CD274 1713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.