SCHEMBL4902016

SCHEMBL4902016

CCCCOCCN1CCN(C)CC1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 2/20 0.47
GNAO1 P09471 2/20 0.47
GNAI1 P63096 2/20 0.47
ALDH1A1 P00352 3/20 0.46
KDM4E B2RXH2 1/20 0.46
HPGD P15428 2/20 0.45
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
TP53 P04637 1/20 0.45
USP2 O75604 2/20 0.45
HRH3 Q9Y5N1 2/20 0.42
DRD3 P35462 1/20 0.42
THRA P10827 1/20 0.42
THRB P10828 1/20 0.42
MAPK1 P28482 2/20 0.42
LTA4H P09960 1/20 0.42
CYP1A2 P05177 1/20 0.42
CHRM2 P08172 1/20 0.42
CHRM1 P11229 1/20 0.42
HTR2A P28223 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19604922 0.96 GNAI3 (0.47) GNAI3GNAO1GNAI1ALDH1A1KDM4E
SCHEMBL23471047 0.94 GNAI3 (0.50) GNAI3GNAO1GNAI1ALDH1A1KDM4E
SCHEMBL19559067 0.94 GNAI3 (0.47) GNAI3GNAO1GNAI1ALDH1A1USP2
SCHEMBL19634433 0.92 GNAI3 (0.53) GNAI3GNAO1GNAI1ALDH1A1KDM4E
SCHEMBL23205258 0.92 GNAI3 (0.49) GNAI3GNAO1GNAI1ALDH1A1KDM4E
SCHEMBL23696579 0.89 HRH2 (0.44) GNAI3GNAO1GNAI1ALDH1A1USP2
SCHEMBL20850750 0.89 GNAI3 (0.44) GNAI3GNAO1GNAI1ALDH1A1KDM4E
SCHEMBL11571542 0.89 HRH3 (0.50) GNAI3GNAO1GNAI1ALDH1A1RAB9A
SCHEMBL21348422 0.88 GNAI3 (0.53) GNAI3GNAO1GNAI1ALDH1A1HPGD
SCHEMBL21477059 0.88 GNAI3 (0.43) GNAI3GNAO1GNAI1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3831841-A1 NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF S&T Global Inc. (US) 2021-06-09 EP disclosed
WO-2017197046-A1 C3-CARBON LINKED GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION C4 THERAPEUTICS, INC. (US) 2017-11-16 WO disclosed
WO-2017197036-A1 SPIROCYCLIC DEGRONIMERS FOR TARGET PROTEIN DEGRADATION C4 THERAPEUTICS, INC. (US) 2017-11-16 WO disclosed
EP-1867667-B1 Method for manufacturing stabilized polyacetal resin POLYPLASTICS CO (JP) 2012-10-31 EP disclosed
US-20080271381-A1 Method for manufacturing stabilized polyacetal resin, stabilized polyacetal resin, stabilized polyacetal resin composition, and molded article of stabilized polyacetal resin POLYPLASTICS CO., LTD (JP) 2008-11-06 US disclosed
EP-1867667-A1 Method for manufacturing stabilized polyacetal resin, stabilized polyacetal resin, stabilized polyacetal resin composition, and molded article of stabilized polyacetal resin Polyplastics Co., Ltd. (JP) 2007-12-19 EP disclosed