Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.33 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.33 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.33 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL67729 | 0.78 | TSHR (0.39) | TSHRORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL9134103 | 0.78 | LTA4H (0.32) | TSHRLTA4H | |
| SCHEMBL10932705 | 0.74 | LMNA (0.44) | TSHR | |
| SCHEMBL151842 | 0.71 | TSHR (0.39) | TSHRORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL130651 | 0.71 | TSHR (0.39) | TSHRORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL2017225 | 0.69 | TSHR (0.35) | TSHRORAI1ORAI2ORAI3TRPV6 | |
| Water SCHEMBL11831397 | 0.69 | TSHR (0.37) | TSHRORAI1ORAI2ORAI3TRPV6 | |
| Hydrochloric Acid SCHEMBL10922114 | 0.69 | TSHR (0.37) | TSHRORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL9746177 | 0.67 | TDP1 (0.33) | TSHRORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL11650376 | 0.67 | CA4 (0.38) | TSHRORAI1ORAI2ORAI3TRPV6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740636-A1 | CATALYSTS AND METHODS FOR POLYMERIZING MACROCYCLIC OLIGOMERS | Dow Gloval Technologies Inc. (US) | 2007-01-10 | — | — | EP | claimed |
| US-20060025562-A1 | Catalysts and methods for polymerizing macrocyclic oligomers | DOW CHEMICAL COMPANY, THE | 2006-02-02 | — | — | US | claimed |
| WO-2005105889-A1 | CATALYSTS AND METHODS FOR POLYMERIZING MACROCYCLIC OLIGOMERS | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2005-11-10 | — | — | WO | claimed |
| US-5461139-A | Ring-opening polymerization of of beta-butyrolactone and cyclic carbonate using distannoxane catalyst | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1995-10-24 | — | — | US | claimed |
| WO-2008021001-A1 | PROCESS FOR PREPARING RUBBER-REINFORCED POLYMER OF CYCLIC MONOMERS | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2008-02-21 | — | — | WO | disclosed |
| US-20080039573-A1 | Polymers of macrocyclic oligomers containing highly expanded graphite | DOW GLOBAL TECHNOLOGIES, INC. | 2008-02-14 | — | — | US | disclosed |
| EP-1773927-A1 | POLYMERIZABLE MACROCYCLIC OLIGOMER MASTERBATCHES CONTAINING DISPERSED FILLERS | Dow Gloval Technologies Inc. (US) | 2007-04-18 | — | — | EP | disclosed |
| US-7196160-B2 | Catalysts and methods for polymerizing macrocyclic oligomers | DOW GLOBAL TECHNOLOGIES INC (US) | 2007-03-27 | — | — | US | disclosed |
| EP-1763558-A1 | METHOD FOR PREPARING NANOCOMPOSITES FROM FILLERS AND MACROCYCLIC OLIGOMERS | Dow Gloval Technologies Inc. (US) | 2007-03-21 | — | — | EP | disclosed |
| EP-1761594-A1 | CATALYST-CONTAINING CLAY MATERIALS FOR COMPOSITES IN POLYMER OF MACROCYCLIC OLIGOMERS | Dow Gloval Technologies Inc. (US) | 2007-03-14 | — | — | EP | disclosed |
| EP-1740636-A1 | CATALYSTS AND METHODS FOR POLYMERIZING MACROCYCLIC OLIGOMERS | Dow Gloval Technologies Inc. (US) | 2007-01-10 | — | — | EP | disclosed |
| WO-2006028541-A1 | POLYMERIZABLE MACROCYCLIC OLIGOMER MASTERBATCHES CONTAINING DISPERSED FILLERS | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2006-03-16 | — | — | WO | disclosed |
| EP-0601885-B1 | Biodegradable optically active polymer of lactones and process for production thereof | TAKASAGO PERFUMERY CO LTD (JP) | 1998-06-03 | — | — | EP | disclosed |
| EP-0612780-B1 | Process for producing poly(3-hydroxybutyric acid) | TAKASAGO PERFUMERY CO LTD (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5516883-A | POLYLACTONES | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5461139-A | Ring-opening polymerization of of beta-butyrolactone and cyclic carbonate using distannoxane catalyst | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1995-10-24 | — | — | US | disclosed |
| US-5430125-A | Ring opening polymerization of beta butyrolalactone in the presence of a distannoxane derivative, a tin carboxylate and a di-lower alkyltin oxide | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1995-07-04 | — | — | US | disclosed |
| EP-0640637-A1 | Biodegradable optically-active polyester carbonates | Takasago International Corporation (JP) | 1995-03-01 | — | — | EP | disclosed |
| EP-0612780-A2 | Process for producing poly(3-hydroxybutyric acid) | Takasago International Corporation (JP) | 1994-08-31 | — | — | EP | disclosed |
| EP-0601885-A2 | Biodegradable optically active polymer of lactones and process for production thereof | Takasago International Corporation (JP) | 1994-06-15 | — | — | EP | disclosed |