Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | LYN | P07948 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4900680 | 0.84 | NOTUM (0.42) | KDM4EMAPK1HTTLMNAMEN1 | |
| SCHEMBL4902508 | 0.84 | ADORA2A (0.45) | KDM4EMAPK1HTTLMNAMEN1 | |
| SCHEMBL4892339 | 0.84 | ADORA2A (0.40) | KDM4EMAPK1HTTLMNAMEN1 | |
| SCHEMBL3582326 | 0.83 | MEN1 (0.52) | KDM4EMAPK1HTTLMNAMEN1 | |
| SCHEMBL4896551 | 0.82 | ADORA2A (0.41) | KDM4EMAPK1HTTLMNAMEN1 | |
| SCHEMBL4896598 | 0.80 | ALDH1A1 (0.43) | KDM4EMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL4895762 | 0.77 | LMNA (0.46) | KDM4EMAPK1LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4901839 | 0.77 | KDM4E (0.45) | KDM4EMAPK1LMNAMEN1KMT2A | |
| SCHEMBL4902868 | 0.77 | CCND3 (0.47) | BTK | |
| SCHEMBL3462062 | 0.75 | LMNA (0.57) | KDM4EMAPK1HTTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080108600-A1 | Polycyclic Pyridines as Potassium Ion Channel Modulators | ICAGEN, INC. (US) | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108600-A1 | Polycyclic Pyridines as Potassium Ion Channel Modulators | KCNJ2, KCNH2, KCNQ1 | KDM4E 542/4885MAPK1 1717/4885HTT 1675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.