Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 10/20 | 0.82 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.82 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4902081 | 1.00 | PTGER4 (0.82) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6165091 | 0.90 | PTGER4 (1.00) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6165089 | 0.90 | PTGER4 (1.00) | PTGER4PTGER3PTGER2 | |
| SCHEMBL10210123 | 0.90 | PTGER4 (1.00) | PTGER4PTGER3PTGER2 | |
| SCHEMBL4909768 | 0.89 | PTGER4 (0.67) | PTGER4PTGER3PTGER2 | |
| SCHEMBL4909782 | 0.89 | PTGER4 (0.67) | PTGER4PTGER3PTGER2 | |
| SCHEMBL4911484 | 0.87 | PTGER4 (0.79) | PTGER4PTGER3PTGER2 | |
| SCHEMBL4911495 | 0.87 | PTGER4 (0.79) | PTGER4PTGER3PTGER2 | |
| SCHEMBL4913586 | 0.85 | PTGER4 (0.65) | PTGER4PTGER3PTGER2 | |
| SCHEMBL4913599 | 0.85 | PTGER4 (0.65) | PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080033033-A1 | 8-AZAPROSTAGLANDIN DERIVATIVES AND MEDICAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. | 2008-02-07 | — | — | US | claimed |
| US-20080033033-A1 | 8-AZAPROSTAGLANDIN DERIVATIVES AND MEDICAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. | 2008-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080033033-A1 | 8-AZAPROSTAGLANDIN DERIVATIVES AND MEDICAL USE THEREOF | HPGDS, PTGIS, PTGER4 | PTGER4 3/4885PTGER3 15/4885PTGER2 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.