Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 17/20 | 0.48 |
| ▸ | LYN | P07948 | 1/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4779949 | 0.87 | MAPK14 (0.37) | BRAFMAPK14 | |
| SCHEMBL4955400 | 0.86 | BRAF (0.42) | BRAFLYNMAPK9MAPK14 | |
| SCHEMBL13436288 | 0.79 | BRAF (0.42) | BRAFLYNMAPK9MAPK14 | |
| SCHEMBL13757145 | 0.78 | BRAF (0.49) | BRAF | |
| SCHEMBL4782863 | 0.78 | NR1I2 (0.40) | BRAFMAPK14 | |
| SCHEMBL4487218 | 0.77 | BRAF (0.51) | BRAFMAPK14 | |
| SCHEMBL4499228 | 0.77 | BRAF (0.48) | BRAFLYNMAPK9 | |
| SCHEMBL4781871 | 0.77 | MAPK14 (0.37) | BRAFMAPK14 | |
| SCHEMBL4489887 | 0.77 | BRAF (0.51) | BRAFMAPK14 | |
| SCHEMBL4487924 | 0.77 | BRAF (0.45) | BRAFLYNMAPK9MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |