Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | TEK | Q02763 | 4/20 | 0.37 |
| ▸ | BRAF | P15056 | 10/20 | 0.35 |
| ▸ | RAF1 | P04049 | 7/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4780817 | 0.91 | NR1I2 (0.36) | NR1I2TEKSCN10AGPR119CNR1 | |
| SCHEMBL4782660 | 0.85 | NR1I2 (0.42) | NR1I2TEKBRAFRAF1SCN10A | |
| SCHEMBL4779949 | 0.84 | MAPK14 (0.37) | NR1I2BRAFMAPK14CNR1 | |
| SCHEMBL4783140 | 0.83 | MAPK14 (0.36) | NR1I2BRAFRAF1MAPK14 | |
| SCHEMBL4880891 | 0.81 | TEK (0.38) | NR1I2TEKBRAFRAF1SCN10A | |
| SCHEMBL4781611 | 0.80 | TEK (0.39) | NR1I2TEKBRAF | |
| SCHEMBL4782191 | 0.80 | MEN1 (0.47) | NR1I2TEKBRAFRAF1 | |
| SCHEMBL14293386 | 0.80 | TEK (0.43) | NR1I2TEKBRAFRAF1 | |
| SCHEMBL4782038 | 0.79 | TEK (0.39) | NR1I2TEKBRAFRAF1GPR119 | |
| SCHEMBL4781875 | 0.79 | SCN10A (0.34) | NR1I2BRAFRAF1SCN10AMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |