SCHEMBL4902187

SCHEMBL4902187

COC(=O)C(F)(F)C(=NOS(C)(=O)=O)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.42
CTRB1 P17538 1/20 0.39
MAPK1 P28482 2/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
KCNN4 O15554 1/20 0.38
GAA P10253 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TSHR P16473 2/20 0.38
ELANE P08246 1/20 0.36
SMN1; SMN2 Q16637 4/20 0.35
POLB P06746 2/20 0.35
MAPT P10636 2/20 0.35
ALDH1A1 P00352 2/20 0.34
HTT P42858 1/20 0.34
HSD17B10 Q99714 1/20 0.34
LMNA P02545 1/20 0.34
ALOX12 P18054 1/20 0.34
CES1 P23141 1/20 0.34
KMT2A Q03164 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4897399 0.86 CES1 (0.36) CTRB1MAPK1L3MBTL1TSHRELANE
SCHEMBL546379 0.82 CES1 (0.40) MAPK1GAAL3MBTL1TSHRPOLB
SCHEMBL546378 0.82 CES1 (0.40) MAPK1GAAL3MBTL1TSHRPOLB
SCHEMBL4895556 0.81 GAA (0.37) MAPK1GAAL3MBTL1TSHRPOLB
SCHEMBL4891641 0.77 KMT2A (0.35) RAB9AGAAL3MBTL1MAPTALDH1A1
SCHEMBL5442975 0.77 KMT2A (0.35) GAAMAPTALDH1A1HSD17B10CES1
SCHEMBL10150826 0.77 SRC (0.41) SRCCTRB1MAPK1NPC1RAB9A
SCHEMBL10186087 0.77 SRC (0.41) SRCCTRB1MAPK1NPC1RAB9A
SCHEMBL4903574 0.76 CES1 (0.32) NPC1RAB9AGAAL3MBTL1SMN1; SMN2
SCHEMBL4903514 0.75 PTGS2 (0.34) CES1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6824954-B2 DIHALOMETHYL SULFONYLOXIME COMPOUNDS; FOR EXAMPLE, 2,2-DIFLUORO-2-METHYLACETOPHENONE-O-METHYLSULFONYLOXIME; HEAT STABILITY AND STORAGE STABILITY; SENSITIVE TO FAR ULTRAVIOLET RADIATION OR ELECTRON BEAMS; RESISTS JSR CORPORATION (JP) 2004-11-30 US claimed
US-20030113660-A1 Sulfonyloxime compound, and radiation sensitive acid generator, positive type radiation sensitive resin composition and negative type radiation sensitive resin composition using same JSR CORPORATION (JP) 2003-06-19 US claimed
US-20080187859-A1 Radiation-Sensitive Resin Composition JSR CORPORATION (JP) 2008-08-07 US disclosed
US-20070269735-A1 Radiation-Sensitive Resin Composition JSR CORPORATION (JP) 2007-11-22 US disclosed
US-7297461-B2 Radiation sensitive resin composition JSR CORPORATION (JP) 2007-11-20 US disclosed
EP-1736829-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2006-12-27 EP disclosed
EP-1726608-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2006-11-29 EP disclosed
US-20050171226-A1 Radiation sensitive resin composition JSR CORPORATION (JP) 2005-08-04 US disclosed
US-6824954-B2 DIHALOMETHYL SULFONYLOXIME COMPOUNDS; FOR EXAMPLE, 2,2-DIFLUORO-2-METHYLACETOPHENONE-O-METHYLSULFONYLOXIME; HEAT STABILITY AND STORAGE STABILITY; SENSITIVE TO FAR ULTRAVIOLET RADIATION OR ELECTRON BEAMS; RESISTS JSR CORPORATION (JP) 2004-11-30 US disclosed
US-20030113660-A1 Sulfonyloxime compound, and radiation sensitive acid generator, positive type radiation sensitive resin composition and negative type radiation sensitive resin composition using same JSR CORPORATION (JP) 2003-06-19 US disclosed