Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 13/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13236911 | 0.84 | SMN1; SMN2 (0.53) | MAOBKDM4ERAB9ASMN1; SMN2POLB | |
| SCHEMBL15380599 | 0.81 | SMN1; SMN2 (0.56) | TAAR1KDM4ERAB9ASMN1; SMN2POLB | |
| SCHEMBL6748837 | 0.80 | SMN1; SMN2 (0.55) | TAAR1KDM4ERAB9ASMN1; SMN2POLB | |
| SCHEMBL12584868 | 0.80 | SMN1; SMN2 (0.58) | TAAR1KDM4ERAB9ASMN1; SMN2POLB | |
| SCHEMBL13719007 | 0.80 | SMN1; SMN2 (0.50) | KDM4ERAB9ASMN1; SMN2POLB | |
| SCHEMBL6238428 | 0.79 | HPGD (0.55) | KDM4ERAB9ASMN1; SMN2POLB | |
| SCHEMBL27850750 | 0.78 | SMN1; SMN2 (0.53) | TAAR1KDM4ERAB9ASMN1; SMN2POLB | |
| SCHEMBL17514795 | 0.77 | SMN1; SMN2 (0.52) | TAAR1KDM4ERAB9ASMN1; SMN2POLB | |
| SCHEMBL29435095 | 0.77 | ITGA4 (0.53) | KDM4ERAB9ASMN1; SMN2POLB | |
| SCHEMBL19715977 | 0.77 | PTPN1 (0.55) | KDM4ERAB9ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101287718-A | Substituted heteroaryl- and phenylsulfamoyl compounds | PFIZER PROD INC (US) | 2008-10-15 | — | — | CN | disclosed |
| US-20080090829-A1 | SUBSTITUTED HETEROARYL- AND PHENYLSULFAMOYL COMPOUNDS | PFIZER INC. | 2008-04-17 | — | — | US | disclosed |
| US-20060229363-A1 | Substituted Heteroaryl- and Phenylsulfamoyl Compounds | HAMANAKA ERNEST S | 2006-10-12 | — | — | US | disclosed |
| US-20050288340-A1 | Substituted heteroaryl- and phenylsulfamoyl compounds | PFIZER INC | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060229363-A1 | Substituted Heteroaryl- and Phenylsulfamoyl Compounds | PPARA, PPARG, PPARD | MAOB 4126/4885TAAR1 2048/4885KDM4E 3750/4885 |
| US-20050288340-A1 | Substituted heteroaryl- and phenylsulfamoyl compounds | PPARA, PPARG, PPARD | MAOB 4263/4885TAAR1 2318/4885KDM4E 3834/4885 |
| US-20080090829-A1 | SUBSTITUTED HETEROARYL- AND PHENYLSULFAMOYL COMPOUNDS | PPARA, PPARG, PPARD | MAOB 4263/4885TAAR1 2318/4885KDM4E 3834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.