Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 12/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.73 |
| ▸ | CCR4 | P51679 | 3/20 | 0.73 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.55 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CCR5 | P51681 | 1/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4916030 | 0.90 | CCR2 (0.76) | CCR2CYP3A4CYP2C9CYP2C19CCR4 | |
| SCHEMBL4907572 | 0.87 | CCR2 (0.78) | CCR2CYP3A4CYP2C9CYP2C19CCR4 | |
| SCHEMBL4910636 | 0.87 | CCR2 (0.74) | CCR2CYP3A4CYP2C9CYP2C19CCR4 | |
| SCHEMBL4911198 | 0.87 | CCR2 (0.74) | CCR2CYP3A4CYP2C9CYP2C19CCR4 | |
| SCHEMBL4913269 | 0.85 | CCR2 (0.82) | CCR2CYP3A4CYP2C9CYP2C19CCR4 | |
| SCHEMBL4902546 | 0.85 | CCR2 (0.78) | CCR2CYP3A4CYP2C9CYP2C19CCR4 | |
| SCHEMBL4902474 | 0.85 | CCR2 (1.00) | CCR2CYP3A4CYP2C9CYP2C19CCR4 | |
| SCHEMBL4913296 | 0.84 | CCR2 (0.71) | CCR2CYP3A4CYP2C9CYP2C19CCR4 | |
| SCHEMBL4910490 | 0.84 | CCR2 (0.71) | CCR2CYP3A4CYP2C9CYP2C19CCR4 | |
| SCHEMBL4907331 | 0.84 | CCR2 (0.71) | CCR2CYP3A4CYP2C9CYP2C19CCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293720-A1 | Pyridinyl Sulfonamide Modulators of Chemokine Receptors | GLAXO GROUP LIMITED (GB) | 2008-11-27 | — | — | US | disclosed |
| US-20080293720-A1 | Pyridinyl Sulfonamide Modulators of Chemokine Receptors | GLAXO GROUP LIMITED (GB) | 2008-11-27 | — | — | US | disclosed |
| US-20080293720-A1 | Pyridinyl Sulfonamide Modulators of Chemokine Receptors | GLAXO GROUP LIMITED (GB) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293720-A1 | Pyridinyl Sulfonamide Modulators of Chemokine Receptors | CCR2, CCR1, CCRL2 | CCR2 1/4885CYP3A4 1414/4885CYP2C9 1296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.