Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.62 |
| ▸ | HPGD | P15428 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | ATM | Q13315 | 3/20 | 0.62 |
| ▸ | GLA | P06280 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | CASP1 | P29466 | 1/20 | 0.62 |
| ▸ | CASP7 | P55210 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 4/20 | 0.53 |
| ▸ | CA2 | P00918 | 4/20 | 0.53 |
| ▸ | CA12 | O43570 | 3/20 | 0.53 |
| ▸ | CA7 | P43166 | 3/20 | 0.53 |
| ▸ | CA9 | Q16790 | 3/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.53 |
| ▸ | XDH | P47989 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9480687 | 0.91 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL977599 | 0.89 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL3112544 | 0.89 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL27707943 | 0.85 | KDM4E (0.58) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL550572 | 0.84 | CA1 (0.57) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL204112 | 0.82 | CA1 (0.55) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL3106288 | 0.82 | KDM4E (0.44) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL3106284 | 0.82 | KDM4E (0.44) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL29492994 | 0.82 | KDM4E (0.69) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL126043 | 0.82 | KDM4E (0.69) | KDM4EALDH1A1HSD17B10HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1129003-A | Reduced fluorescence compositions containing naphthalenedicarboxylic acid polymers and halogens | EASTMAN CHEM CO (US) | 1996-08-14 | — | — | CN | claimed |
| US-20140135327-A1 | N- (2 -AMINOPHENYL) BENZAMIDE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2014-05-15 | — | — | US | disclosed |
| US-20140135327-A1 | N- (2 -AMINOPHENYL) BENZAMIDE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2014-05-15 | — | — | US | disclosed |
| US-20140135327-A1 | N- (2 -AMINOPHENYL) BENZAMIDE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2014-05-15 | — | — | US | disclosed |
| EP-2729450-A1 | N- (2 -AMINOPHENYL) BENZAMIDE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | Cancer Research Technology Ltd (GB) | 2014-05-14 | — | — | EP | disclosed |
| WO-2013005049-A1 | N- (2 -AMINOPHENYL) BENZAMIDE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2013-01-10 | — | — | WO | disclosed |
| US-8350041-B2 | Tricyclic δ-opioid modulators | JANSSEN PHARMACEUTICA, NV (BE) | 2013-01-08 | — | — | US | disclosed |
| US-20120095010-A1 | TRICYCLIC DELTA-OPIOID MODULATORS | CARSON JOHN R (US) | 2012-04-19 | — | — | US | disclosed |
| US-8106207-B2 | Tricyclic δ-opioid modulators | JANSSEN PHARMACEUTICA, NV (BE) | 2012-01-31 | — | — | US | disclosed |
| US-20110245291-A1 | TRICYCLIC DELTA-OPIOID MODULATORS | CARSON JOHN R | 2011-10-06 | — | — | US | disclosed |
| WO-2001081316-A2 | SUBSTITUTED PHENYL FARNESYLTRANSFERASE INHIBITORS | ABBOTT LABORATORIES (US) | 2001-11-01 | — | — | WO | disclosed |
| US-5880309-A | DIALKYL DIALKOXYCARBONYLPHENYL PHOSPHONATES USEFUL AS RESIN MODIFIERS PRODUCED AT HIGH YIELD AND LOW COST BY HEATING A TRIALKYL PHOSPHITE AND A DIALKOXYCARBONYLPHENYL HALIDE IN THE PRESENCE OF A PALLADIUM OR NICKEL CATALYST AND HYDROLYZING | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-03-09 | — | — | US | disclosed |
| CN-1209146-A | Polymeric fluorescence quenching compounds and their use | EASTMAN CHEM CO (US) | 1999-02-24 | — | — | CN | disclosed |
| CN-1209150-A | Polyester blend compositions containing naphthalene dicarboxylate having reduced fluorescence | EASTMAN CHEM CO (US) | 1999-02-24 | — | — | CN | disclosed |
| EP-0873123-A4 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 1999-02-03 | — | — | EP | disclosed |
| EP-0873123-A1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1998-10-28 | — | — | EP | disclosed |
| EP-0855400-A1 | Phenylphosphonic acid derivative and production process therefor | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |
| WO-1997017070-A1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1997-05-15 | — | — | WO | disclosed |
| CN-1129003-A | Reduced fluorescence compositions containing naphthalenedicarboxylic acid polymers and halogens | EASTMAN CHEM CO (US) | 1996-08-14 | — | — | CN | disclosed |
| CN-1129006-A | Process for prepn. of naphthalenedicarboxylic acid containing polymer blends having reduced fluorescence | EASTMAN CHEM CO (US) | 1996-08-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140135327-A1 | N- (2 -AMINOPHENYL) BENZAMIDE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | HDAC5, HDAC2, HDAC1 | KDM4E 318/4885ALDH1A1 186/4885HSD17B10 1180/4885 |
| US-20120095010-A1 | TRICYCLIC DELTA-OPIOID MODULATORS | OPRD1, OPRK1, OPRL1 | KDM4E 2174/4885ALDH1A1 1302/4885HSD17B10 1523/4885 |
| US-20110245291-A1 | TRICYCLIC DELTA-OPIOID MODULATORS | OPRD1, OPRK1, OPRL1 | KDM4E 2174/4885ALDH1A1 1302/4885HSD17B10 1523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.