Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 5/20 | 0.45 |
| ▸ | ACHE | P22303 | 5/20 | 0.45 |
| ▸ | MAOB | P27338 | 5/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24012573 | 0.94 | HDAC3 (0.45) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL5672847 | 0.87 | MCHR1 (0.45) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL5743428 | 0.86 | MAOB (0.51) | BCHEACHEMAOBMAOA | |
| SCHEMBL6041286 | 0.80 | KDM4E (0.54) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL23014971 | 0.80 | KDM4E (0.54) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL8435356 | 0.80 | KDM4E (0.54) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL5675347 | 0.79 | MAOB (0.49) | KDM4ETSHRBCHEACHEMAOB | |
| SCHEMBL5867104 | 0.79 | LMNA (0.56) | KDM4ELMNABCHEACHEMAOB | |
| SCHEMBL11673147 | 0.79 | HDAC3 (0.62) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL2658522 | 0.78 | KDM4E (0.56) | KDM4EUSP2ALDH1A1LMNAMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080318255-A1 | Fluorescent Labeled Sphingosines | BILLICH ANDREAS | 2008-12-25 | — | — | US | disclosed |
| EP-1670807-A1 | FLUORESCENT LABELED SPHINGOSINES | Novartis AG (CH) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005030780-A1 | FLUORESCENT LABELED SPHINGOSINES | NOVARTIS AG (CH) | 2005-04-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080318255-A1 | Fluorescent Labeled Sphingosines | SPHK1, SPHK2, SGPL1 | HDAC3 1606/4885HDAC1 1790/4885HDAC2 1614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.