Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 5/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | OXTR | P30559 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4713988 | 0.91 | AVPR1A (0.42) | CCR5CYP2D6LMNAAVPR1AGALR3 | |
| SCHEMBL4711858 | 0.83 | AVPR1A (0.44) | CYP2D6LMNAAVPR1ARAB9ATSHR | |
| SCHEMBL4711275 | 0.81 | DRD2 (0.46) | AVPR1AOXTRCYP3A4 | |
| SCHEMBL4711335 | 0.80 | OPRM1 (0.58) | CYP2D6LMNAMAPK1OPRM1OPRD1 | |
| SCHEMBL5155966 | 0.75 | AVPR1A (0.48) | CYP2D6AVPR1AOXTRKMT2ATRPA1 | |
| SCHEMBL8256810 | 0.75 | AVPR1A (0.48) | CYP2D6AVPR1ATSHROXTRMEN1 | |
| Hydrochloric Acid SCHEMBL5156223 | 0.74 | AVPR1A (0.47) | CYP2D6AVPR1ATSHROXTRMEN1 | |
| Hydrochloric Acid SCHEMBL315285 | 0.74 | AVPR1A (0.47) | CYP2D6AVPR1ATSHROXTRMEN1 | |
| SCHEMBL4760978 | 0.74 | AVPR1A (0.47) | AVPR1AOXTRTRPA1TRPM8 | |
| SCHEMBL4714355 | 0.74 | AVPR1A (0.47) | AVPR1AOXTRTRPA1TRPM8CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080188478-A1 | Compounds Useful In Therapy | PFIZER INC. | 2008-08-07 | — | — | US | claimed |
| US-20080188478-A1 | Compounds Useful In Therapy | PFIZER INC. | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188478-A1 | Compounds Useful In Therapy | AVPR1A, AVPR1B, AVPR2 | CCR5 1132/4885CYP2D6 451/4885LMNA 2648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.