Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5133124 | 0.79 | TAS1R3 (0.50) | ALDH1A1RIPK1TAS1R3TAS1R1HDAC8 | |
| SCHEMBL5463519 | 0.79 | UTS2R (0.46) | HTR2AHRH1UTS2R | |
| SCHEMBL4237262 | 0.78 | TAS1R3 (0.45) | HTR2AALDH1A1RIPK1TAS1R3TAS1R1 | |
| SCHEMBL4731821 | 0.78 | HTR2A (0.42) | HTR2AHRH1RIPK1AOC3 | |
| SCHEMBL6829520 | 0.78 | AOC3 (0.58) | HTR2AHRH1AOC3 | |
| SCHEMBL5454333 | 0.78 | AOC3 (0.58) | HTR2AHRH1AOC3UTS2R | |
| SCHEMBL4733883 | 0.78 | CHRM2 (0.49) | HTR2AHRH1UTS2R | |
| SCHEMBL188905 | 0.78 | HTR2A (0.42) | HTR2AHRH1ALDH1A1RIPK1AOC3 | |
| SCHEMBL31572076 | 0.78 | AOC3 (0.58) | HTR2AHRH1AOC3 | |
| SCHEMBL1534201 | 0.77 | HTR2A (0.67) | HTR2AHRH1ALDH1A1RIPK1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080003288-A1 | Responsive microgel and methods related thereto | SUPRATEK PHARMA INC. (CA) | 2008-01-03 | — | — | US | disclosed |
| US-7204997-B2 | Responsive microgel and methods related thereto | SUPRATEK PHARMA INC. (CA) | 2007-04-17 | — | — | US | disclosed |
| US-20030152623-A1 | Responsive microgel and methods related thereto | SUPRATEK PHARMA INC. (CA) | 2003-08-14 | — | — | US | disclosed |
| EP-0910351-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. Searle & Co. (US) | 1999-04-28 | — | — | EP | disclosed |
| WO-1997049387-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. SEARLE AND CO. (US) | 1997-12-31 | — | — | WO | disclosed |
| EP-0282623-B1 | SYNTHETIC POLYMERS WITH GLYCOSIDE SIDE CHAINS | National Starch and Chemical Investment Holding Corporation (US) | 1990-09-26 | — | — | EP | disclosed |
| EP-0282623-A1 | Synthetic polymers with glycoside side chains | National Starch and Chemical Investment Holding Corporation (US) | 1988-09-21 | — | — | EP | disclosed |
| US-4673707-A | REACTING SYNTHETIC POLYMERS WITH HALOHYDRIN GLYCOSIDE OF SACCHARIDES | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1987-06-16 | — | — | US | disclosed |