SCHEMBL4903560

SCHEMBL4903560

COc1cc(C(=O)O)c(C)c(OC)c1OC

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.58
LCK P06239 1/20 0.52
FYN P06241 1/20 0.52
KDM4E B2RXH2 7/20 0.50
POLB P06746 2/20 0.50
TPMT P51580 1/20 0.49
MAPT P10636 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
MYC P01106 1/20 0.47
ALDH1A1 P00352 5/20 0.46
HSD17B10 Q99714 4/20 0.46
HPGD P15428 4/20 0.46
USP2 O75604 1/20 0.46
LMNA P02545 1/20 0.46
PTPN1 P18031 1/20 0.44
ACHE P22303 1/20 0.43
HTR1A P08908 1/20 0.43
HTR2C P28335 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL27859010 0.98 PKM (0.57) PKMLCKFYNKDM4EPOLB
Methyl Syringate SCHEMBL5152857 0.87 KDM4E (0.51) PKMKDM4EPOLBTPMTMAPT
SCHEMBL383326 0.87 PKM (0.46) PKMLCKFYNKDM4EPOLB
SCHEMBL159393 0.85 MAPT (0.54) PKMLCKFYNKDM4EPOLB
SCHEMBL1438926 0.84 PKM (0.62) PKMLCKFYNKDM4EPOLB
SCHEMBL27731624 0.84 HSD17B10 (0.52) PKMLCKFYNKDM4EPOLB
SCHEMBL437132 0.84 LCK (0.56) PKMLCKFYNKDM4EPOLB
SCHEMBL30740970 0.84 LCK (0.56) PKMLCKFYNKDM4EPOLB
SCHEMBL505418 0.84 LCK (0.56) PKMLCKFYNKDM4ETPMT
SCHEMBL12135968 0.83 KDM4E (0.67) PKMKDM4EPOLBALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016079759-A1 NOVEL SINGLE STEP ESTERIFICATION PROCESS OF ALDEHYDES USING A HETEROGENEOUS CATALYST COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2016-05-26 WO disclosed
WO-2012145518-A1 NONTOXIC OBSCURANT COMPOSITIONS AND METHOD OF USING SAME LOMBARDI JOHN L (US) 2012-10-26 WO disclosed
US-20120267016-A1 Nontoxic Obscurant Compositions and Method of Using Same LOMBARDI JOHN L (US) 2012-10-25 US disclosed
US-20080292715-A1 Unique Manuka Factor (Umf) Fortified Honey WAIKATO THE UNIVERSITY OF (NZ) 2008-11-27 US disclosed
EP-1771087-A4 UNIQUE MANUKA FACTOR (UMF) FORTIFIED HONEY UNIV WAIKATO (NZ) 2007-10-03 EP disclosed
CN-1980577-A Unique manuka factor (UMF) fortified honey UNIV WAIKATO (NZ) 2007-06-13 CN disclosed
CN-1317277-C Benzofuran derivatives and their use as pharmaceutical preparations ARPIDA AG (CH) 2007-05-23 CN disclosed
EP-1771087-A1 UNIQUE MANUKA FACTOR (UMF) FORTIFIED HONEY The University of Waikato (NZ) 2007-04-11 EP disclosed
WO-2005120250-A1 UNIQUE MANUKA FACTOR (UMF) FORTIFIED HONEY THE UNIVERSITY OF WAIKATO (NZ) 2005-12-22 WO disclosed
CN-1440404-A Benzofuran derivatives and their use as antibacterial agents ARPIDA AG (CH) 2003-09-03 CN disclosed
US-4052553-A BACTERICIDE, ANTIMALARIAL BURROUGHS WELLCOME CO. (US) 1977-10-04 US disclosed