SCHEMBL383326

SCHEMBL383326

COc1c(OCl)cc(C(=O)O)c(C)c1OC

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.46
LCK P06239 1/20 0.43
FYN P06241 1/20 0.43
HSD17B10 Q99714 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
MAPT P10636 1/20 0.41
MYC P01106 1/20 0.41
KDM4E B2RXH2 6/20 0.39
POLB P06746 2/20 0.39
ALDH1A1 P00352 3/20 0.38
HPGD P15428 2/20 0.38
TPMT P51580 2/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
NOTUM Q6P988 1/20 0.37
HTR1A P08908 1/20 0.37
HTR2C P28335 1/20 0.37
USP2 O75604 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4903560 0.87 PKM (0.58) PKMLCKFYNHSD17B10TDP1
Ammonia Solution, Strong SCHEMBL27859010 0.86 PKM (0.57) PKMLCKFYNHSD17B10TDP1
SCHEMBL27731624 0.83 HSD17B10 (0.52) PKMLCKFYNHSD17B10TDP1
SCHEMBL31012417 0.78 HSD17B10 (0.46) PKMLCKFYNHSD17B10TDP1
SCHEMBL15573104 0.78 HSD17B10 (0.46) PKMLCKFYNHSD17B10TDP1
SCHEMBL159393 0.77 MAPT (0.54) PKMLCKFYNHSD17B10TDP1
SCHEMBL670626 0.77 TPMT (0.49) PKMLCKFYNHSD17B10TDP1
Methyl Syringate SCHEMBL5152857 0.76 KDM4E (0.51) PKMHSD17B10MAPTKDM4EPOLB
SCHEMBL505418 0.76 LCK (0.56) PKMLCKFYNHSD17B10TDP1
SCHEMBL27711069 0.75 HSD17B10 (0.55) PKMLCKFYNHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2545973-B1 ORGANOMETALLIC COMPOUND PURIFICATION BY STRIPPING STEP DOW GLOBAL TECHNOLOGIES LLC (US) 2020-03-04 EP disclosed
EP-2559682-B1 Organometallic compound preparation ROHM & HAAS ELECT MAT (US) 2016-08-03 EP disclosed
US-9403145-B2 Organometallic compound preparation DOW GLOBAL TECHNOLOGIES LLC (US) 2016-08-02 US disclosed
EP-2559681-B1 Organometallic compound preparation DOW GLOBAL TECHNOLOGIES LLC (US) 2016-06-22 EP disclosed
US-20150174552-A1 ORGANOMETALLIC COMPOUND PREPARATION ROHM AND HAAS ELECTRONIC MATERIALS LLC 2015-06-25 US disclosed
US-9006475-B2 Organometallic compound preparation ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2015-04-14 US disclosed
US-8969608-B2 Organometallic compound preparation DOW GLOBAL TECHNOLOGIES LLC (US) 2015-03-03 US disclosed
US-8901335-B2 Organometallic compound purification and apparatus DOW GLOBAL TECHNOLOGIES LLC (US) 2014-12-02 US disclosed
US-20130211117-A1 ORGANOMETALLIC COMPOUND PREPARATION DOW GLOBAL TECHNOLOGIES LLC (US) 2013-08-15 US disclosed
US-20130211118-A1 ORGANOMETALLIC COMPOUND PREPARATION ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2013-08-15 US disclosed
US-20110172452-A1 Method of Preparing Organometallic Compounds ROHM AND HAAS COMPANY (US) 2011-07-14 US disclosed
US-7939684-B2 Method of preparing organometallic compounds ROHM AND HAAS COMPANY (US) 2011-05-10 US disclosed
US-7919638-B2 Method of preparing organometallic compounds ROHM AND HAAS COMPANY (US) 2011-04-05 US disclosed
US-20100185003-A1 Method of Preparing Organometallic Compounds ROHM AND HAAS COMPANY (US) 2010-07-22 US disclosed
US-20100185002-A1 Method of Preparing Organometallic Compounds ROHM AND HAAS COMPANY (US) 2010-07-22 US disclosed
US-7659414-B2 Method of preparing organometallic compounds ROHM AND HAAS COMPANY (US) 2010-02-09 US disclosed
EP-2020257-A2 Purification Process Using Microchannel Devices Rohm and Haas Company (US) 2009-02-04 EP disclosed
EP-2020258-A2 Method Of Preparing Organometallic Compounds Rohm and Haas Company (US) 2009-02-04 EP disclosed
US-20090023940-A1 Method of preparing organometallic compounds ROHM AND HAAS COMPANY 2009-01-22 US disclosed
US-20090020010-A1 Purification process using microchannel devices ROHM AND HAAS COMPANY 2009-01-22 US disclosed