Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CHIT1 | Q13231 | 5/20 | 0.38 |
| ▸ | CHIA | Q9BZP6 | 5/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | CHI3L1 | P36222 | 1/20 | 0.38 |
| ▸ | CHI3L2 | Q15782 | 1/20 | 0.38 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2761949 | 0.86 | HDAC1 (0.46) | DRD3NPC1RAB9ASLC6A2SLC6A4 | |
| SCHEMBL3075455 | 0.81 | CHIA (0.43) | CHIT1CHIAGRIN2BCHI3L1CHI3L2 | |
| SCHEMBL3085819 | 0.76 | SIGMAR1 (0.48) | — | |
| SCHEMBL9283021 | 0.74 | HRH3 (0.56) | DPP4SLC6A2SLC6A4SLC6A3PLA2G10 | |
| SCHEMBL13163598 | 0.73 | HDAC1 (0.49) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL3697068 | 0.73 | OPRM1 (0.57) | GRIN2BSLC6A2SLC6A3 | |
| SCHEMBL3090217 | 0.71 | HRH3 (0.64) | PLA2G10PLA2G2A | |
| SCHEMBL2762220 | 0.71 | BCL2A1 (0.38) | PIK3CD | |
| Hydrochloric Acid SCHEMBL28918864 | 0.70 | HRH3 (0.62) | PLA2G10PLA2G2A | |
| SCHEMBL13163590 | 0.70 | HDAC1 (0.47) | NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080108611-A1 | SUBSTITUTED THIENOPYRIMIDINE KINASE INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-05-08 | — | — | US | claimed |
| WO-2007084815-A2 | SUBSTITUTED THIENOPYRIMIDINE KINASE INHIBITORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-07-26 | — | — | WO | claimed |
| US-20080108611-A1 | SUBSTITUTED THIENOPYRIMIDINE KINASE INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-05-08 | — | — | US | disclosed |
| WO-2007084815-A2 | SUBSTITUTED THIENOPYRIMIDINE KINASE INHIBITORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-07-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108611-A1 | SUBSTITUTED THIENOPYRIMIDINE KINASE INHIBITORS | MAP4K2, MAP3K6, MAP3K2 | DRD3 4864/4885MAOB 1944/4885CHIT1 4729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.