Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | STS | P08842 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4912573 | 0.88 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9AHTTGPR119 | |
| SCHEMBL9008880 | 0.86 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1RAB9AHTTGPR119 | |
| SCHEMBL785781 | 0.86 | CCR5 (0.58) | GPR119JAK2JAK1STS | |
| SCHEMBL13797803 | 0.84 | GPR119 (0.57) | GPR119KDM4EPKMJAK2JAK1 | |
| SCHEMBL6967998 | 0.83 | SMN1; SMN2 (0.60) | SMN1; SMN2NPC1RAB9AHTTGPR119 | |
| SCHEMBL27099041 | 0.83 | SMN1; SMN2 (0.56) | YAP1SMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL23249889 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2NPC1RAB9AHTTGPR119 | |
| SCHEMBL16095616 | 0.82 | GPR119 (0.48) | YAP1SMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL4915131 | 0.81 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9AHTTGPR119 | |
| SCHEMBL6976534 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2NPC1RAB9AHTTGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200460-A1 | Chemical Compounds | BROWN DEARG | 2008-08-21 | — | — | US | disclosed |
| US-20080200460-A1 | Chemical Compounds | BROWN DEARG | 2008-08-21 | — | — | US | disclosed |
| US-20080200460-A1 | Chemical Compounds | BROWN DEARG | 2008-08-21 | — | — | US | disclosed |
| EP-1833792-A1 | SUBSTITUTED PIPERIDINE COMPOUNDS FOR USE AS CCR5 MODULATORS | AstraZeneca AB (SE) | 2007-09-19 | — | — | EP | disclosed |
| WO-2006067385-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2006-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200460-A1 | Chemical Compounds | CCR5, CXCR4, CXCR5 | YAP1 1123/4885SMN1; SMN2 3791/4885NPC1 1430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.