SCHEMBL4904490

SCHEMBL4904490

C=CCc1ccc(C(C=O)OC)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
CYP3A4 P08684 3/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
TP53 P04637 1/20 0.50
ALOX15 P16050 1/20 0.50
TSHR P16473 1/20 0.50
ALOX12 P18054 1/20 0.50
PPARG P37231 1/20 0.42
PPARD Q03181 1/20 0.42
PPARA Q07869 1/20 0.42
PTGS1 P23219 2/20 0.39
TRPM8 Q7Z2W7 2/20 0.39
ALOX5 P09917 2/20 0.39
AR P10275 1/20 0.39
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
KDM4E B2RXH2 1/20 0.37
LMNA P02545 1/20 0.37
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5958618 0.79 CA1 (0.33) CYP1A2CYP2D6L3MBTL1ESR1ESR2
SCHEMBL10455686 0.77 ALDH1A1 (0.46) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
SCHEMBL7785443 0.74 ALDH1A1 (0.47) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
SCHEMBL7732432 0.72 ALDH1A1 (0.42) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
SCHEMBL3412742 0.72 SLC6A4 (0.41) TP53ALOX15TSHRLMNAMAPK1
SCHEMBL5256023 0.72 AOC3 (0.41) ALDH1A1LMNAGAAMAPTHTT
SCHEMBL29207873 0.72 ALDH1A1 (0.48) ALDH1A1TSHRMEN1KMT2ACYP1A2
SCHEMBL7193434 0.71 ALDH1A1 (0.52) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
SCHEMBL1158419 0.71 KMT2A (0.47) ALDH1A1CYP3A4TSHRKMT2ALMNA
SCHEMBL14686443 0.71 KMT2A (0.47) ALDH1A1CYP3A4TSHRKMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080032913-A1 Masking of mineral oil odor and fragrancing of mineral oils SYMRISE GMBH & CO. KG (DE) 2008-02-07 US claimed