Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL173301 | 0.75 | ALDH1A1 (0.64) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 | |
| SCHEMBL4904490 | 0.74 | ALDH1A1 (0.50) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 | |
| SCHEMBL10345728 | 0.74 | ACACB (0.38) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 | |
| SCHEMBL9636753 | 0.73 | ALDH1A1 (0.48) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 | |
| SCHEMBL20636612 | 0.73 | GABRA1 (0.42) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 | |
| SCHEMBL7193434 | 0.72 | ALDH1A1 (0.52) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 | |
| SCHEMBL28381315 | 0.72 | CHRNA7 (0.43) | ALDH1A1SMN1; SMN2MAPTMEN1GAA | |
| SCHEMBL9578892 | 0.72 | ALDH1A1 (0.52) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 | |
| SCHEMBL8407914 | 0.72 | MEN1 (0.36) | ALDH1A1CYP3A4TP53TSHRMAPT | |
| Phosphine SCHEMBL28908227 | 0.72 | ALDH1A1 (0.61) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140756-A2 | SYNTHESIS OF DIHYDROHONOKIOL COMPOSITIONS | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040532-A2 | SYNTHESIS OF DIHYDROHONOKIOL COMPOSITIONS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2000-07-13 | — | — | WO | disclosed |
| EP-0991614-A1 | SYNTHESIS OF DIHYDROHONOKIOL COMPOSITIONS | Board of Regents, The University of Texas System (US) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999000346-A1 | SYNTHESIS OF DIHYDROHONOKIOL COMPOSITIONS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1999-01-07 | — | — | WO | disclosed |