Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 8/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 8/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 8/20 | 0.42 |
| ▸ | F7 | P08709 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4877744 | 1.00 | KMT2A (0.44) | KMT2AMEN1ALDH1A1MMP9MMP8 | |
| SCHEMBL1109551 | 0.92 | MEN1 (0.46) | KMT2AMEN1ALDH1A1HDAC3HDAC4 | |
| SCHEMBL1109494 | 0.92 | MEN1 (0.46) | KMT2AMEN1ALDH1A1HDAC3HDAC4 | |
| SCHEMBL4877739 | 0.91 | MEN1 (0.45) | KMT2AMEN1ALDH1A1HDAC3HDAC4 | |
| SCHEMBL4904520 | 0.91 | MEN1 (0.45) | KMT2AMEN1ALDH1A1HDAC3HDAC4 | |
| SCHEMBL436268 | 0.90 | MEN1 (0.44) | KMT2AMEN1HDAC3HDAC4HDAC1 | |
| SCHEMBL404287 | 0.90 | MEN1 (0.44) | KMT2AMEN1HDAC3HDAC4HDAC1 | |
| SCHEMBL400694 | 0.88 | MEN1 (0.42) | KMT2AMEN1HDAC3HDAC4HDAC1 | |
| SCHEMBL405616 | 0.88 | MEN1 (0.42) | KMT2AMEN1HDAC3HDAC4HDAC1 | |
| SCHEMBL4233159 | 0.81 | HDAC8 (0.38) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358359-B2 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2008-04-15 | — | — | US | disclosed |
| US-20060154988-A1 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2006-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060154988-A1 | Antibacterial agents | MRPL21, SI, PGLS | KMT2A 4800/4885MEN1 2414/4885ALDH1A1 782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.