Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL230205 | 0.90 | LMNA (0.74) | LMNAALDH1A1KDM4EUSP2HPGD | |
| SCHEMBL230518 | 0.79 | LMNA (0.75) | LMNAALDH1A1KDM4EUSP2HPGD | |
| SCHEMBL30754392 | 0.79 | ALDH1A1 (0.75) | LMNAALDH1A1KDM4EUSP2HPGD | |
| SCHEMBL29436053 | 0.77 | ALDH1A1 (0.76) | LMNAALDH1A1KDM4EUSP2HPGD | |
| SCHEMBL230563 | 0.77 | ALDH1A1 (0.76) | LMNAALDH1A1KDM4EUSP2HPGD | |
| SCHEMBL232305 | 0.76 | ALDH1A1 (0.70) | LMNAALDH1A1KDM4EUSP2HPGD | |
| SCHEMBL12522776 | 0.76 | LMNA (0.70) | LMNAALDH1A1KDM4EUSP2HPGD | |
| SCHEMBL230185 | 0.75 | ALDH1A1 (0.80) | LMNAALDH1A1KDM4EUSP2HPGD | |
| SCHEMBL14881297 | 0.75 | ALDH1A1 (0.63) | LMNAALDH1A1KDM4EUSP2HPGD | |
| SCHEMBL11542238 | 0.75 | ALDH1A1 (0.63) | LMNAALDH1A1KDM4EUSP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937242-A2 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF NEUROPSYCHIATRIC AND ADDICTIVE DISORDERS | NeuroTherapeutics Pharma, Inc. (US) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007047698-A2 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF NEUROPSYCHIATRIC AND ADDICTIVE DISORDERS | NEUROTHERAPEUTICS PHARMA, INC. (US) | 2007-04-26 | — | — | WO | disclosed |