Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 7/20 | 0.74 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30587417 | 0.87 | BCHE (0.72) | BCHEGAAKMT2AALDH1A1MAPK1 | |
| SCHEMBL30587413 | 0.87 | BCHE (0.72) | BCHEGAAKMT2AALDH1A1MAPK1 | |
| SCHEMBL5047341 | 0.86 | BCHE (0.70) | BCHEGAAKMT2AALDH1A1MAPK1 | |
| SCHEMBL14144415 | 0.84 | BCHE (0.88) | BCHEGAAKMT2AALDH1A1MAPK1 | |
| Bromide SCHEMBL10777395 | 0.84 | BCHE (0.97) | BCHEGAAKMT2AALDH1A1MAPK1 | |
| SCHEMBL3844246 | 0.83 | ALDH1A1 (0.53) | BCHEALDH1A1SMN1; SMN2 | |
| SCHEMBL12155343 | 0.81 | BCHE (0.77) | BCHEGAAKMT2AALDH1A1MAPK1 | |
| SCHEMBL3842797 | 0.80 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL3518696 | 0.79 | BCHE (0.65) | BCHEGAAKMT2AALDH1A1MAPK1 | |
| SCHEMBL14524626 | 0.79 | BCHE (0.65) | BCHEGAAKMT2AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931341-A2 | NOVEL 1H-INDOLE-PYRIDINECARBOXAMIDE DERIVATIVES AND 1H-INDOLE-PIPERIDINECARBOXAMIDE AND THEIR USE AS HYDROXALASE TYROSINE INDUCERS | Les Laboratoires Servier (FR) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007006922-A2 | NOVEL 1H-INDOLE-PYRIDINECARBOXAMIDE DERIVATIVES AND 1H-INDOLE-PIPERIDINECARBOXAMIDE AND THEIR USE AS HYDROXYLASE TYROSINE INDUCERS | LES LABORATOIRES SERVIER (FR) | 2007-01-18 | — | — | WO | disclosed |