Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 8/20 | 0.50 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.49 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4803854 | 0.78 | FDPS (0.44) | FDPSGGPS1BTN3A1CA12CA2 | |
| SCHEMBL12474925 | 0.76 | FDPS (0.47) | FDPSGGPS1BTN3A1CA12CA2 | |
| SCHEMBL3896437 | 0.75 | FDPS (0.46) | FDPSGGPS1BTN3A1CA12CA2 | |
| Water SCHEMBL5555771 | 0.69 | FDPS (0.43) | FDPSGGPS1BTN3A1CA12CA2 | |
| SCHEMBL2523006 | 0.69 | — | — | |
| SCHEMBL6692416 | 0.69 | — | — | |
| Zoledronic Acid Anhydrous SCHEMBL1586366 | 0.67 | FDPS (1.00) | FDPSGGPS1BTN3A1CA12CA2 | |
| Zoledronic Acid Anhydrous SCHEMBL19054 | 0.67 | FDPS (1.00) | FDPSGGPS1BTN3A1CA12CA2 | |
| SCHEMBL17124811 | 0.66 | CYP11B1 (0.48) | CA2LMNACYP11B1CYP11B2TBXAS1 | |
| Zoledronic Acid Anhydrous SCHEMBL515095 | 0.66 | FDPS (0.96) | FDPSGGPS1BTN3A1CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312440-A1 | SYNTHESIS OF DRUG CONJUGATES VIA REACTION WITH EPOXIDE-CONTAINING LINKERS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2008-12-18 | — | — | US | claimed |
| US-20180362559-A1 | BONE ACTIVE NITROGEN-CONTAINING BISPHOSPHONATES WITH A NEAR INFRARED FLUORESCENT LABEL | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2018-12-20 | — | — | US | disclosed |
| WO-2017053486-A1 | BONE ACTIVE NITROGEN-CONTAINING BISPHOSPHONATES WITH A NEAR INFRARED FLUORESCENT LABEL | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2017-03-30 | — | — | WO | disclosed |
| US-20130203998-A1 | Synthesis of Drug Conjugates Via Reaction With Epoxide-Containing Linkers | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2013-08-08 | — | — | US | disclosed |
| US-8431714-B2 | Synthesis of drug conjugates via reaction with epoxide-containing linkers | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2013-04-30 | — | — | US | disclosed |
| US-20080312440-A1 | SYNTHESIS OF DRUG CONJUGATES VIA REACTION WITH EPOXIDE-CONTAINING LINKERS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312440-A1 | SYNTHESIS OF DRUG CONJUGATES VIA REACTION WITH EPOXIDE-CONTAINING LINKERS | EPHX2, EPHX1, ENPP1 | FDPS 58/4885GGPS1 14/4885BTN3A1 3840/4885 |
| US-20180362559-A1 | BONE ACTIVE NITROGEN-CONTAINING BISPHOSPHONATES WITH A NEAR INFRARED FLUORESCENT LABEL | PTH1R, BMP2, CALCR | FDPS 1415/4885GGPS1 110/4885BTN3A1 1354/4885 |
| US-20130203998-A1 | Synthesis of Drug Conjugates Via Reaction With Epoxide-Containing Linkers | EPHX2, EPHX1, ENPP1 | FDPS 58/4885GGPS1 14/4885BTN3A1 3840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.