Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 9/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27886223 | 0.82 | ADORA2A (0.51) | ADORA2AHSD17B10ADRA2AHTTADORA1 | |
| SCHEMBL27886231 | 0.82 | ADORA2A (0.51) | ADORA2AHSD17B10ADRA2AHTTADORA1 | |
| SCHEMBL7011406 | 0.80 | ADORA2A (0.70) | ADORA2AHSD17B10ADRA2AHTTADORA1 | |
| SCHEMBL17971419 | 0.80 | ADORA2A (0.53) | ADORA2AHSD17B10ADRA2AHTTADORA1 | |
| SCHEMBL7219735 | 0.78 | GRM5 (0.51) | ADORA2AHSD17B10HTTADORA1KDM4E | |
| SCHEMBL23579403 | 0.77 | USP7 (0.49) | ADORA2AADORA1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL13202793 | 0.76 | ADORA2A (0.49) | ADORA2AHSD17B10ADRA2AHTTADORA1 | |
| SCHEMBL3205196 | 0.76 | ALDH1A1 (0.59) | ADORA2AHSD17B10ADORA1KDM4EALDH1A1 | |
| SCHEMBL16740138 | 0.75 | ADORA2A (0.48) | ADORA2AHSD17B10ADRA2AHTTADORA1 | |
| SCHEMBL3544893 | 0.75 | ADORA2A (0.62) | ADORA2AHSD17B10ADRA2AHTTADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109020883-B | 3-cyano-2-aminopyridine derivative and preparation method and application thereof | 广西民族大学 | 2022-02-08 | — | — | CN | disclosed |
| US-20080139608-A1 | 2,6,8, Trisubstituted 1-deazapurines and their different uses | UNIVERSITEIT LEIDEN (NL) | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139608-A1 | 2,6,8, Trisubstituted 1-deazapurines and their different uses | TPMT, NAT1, MTAP | ADORA2A 142/4885HSD17B10 645/4885ADRA2A 2210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.