Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 10/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 9/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1821593 | 0.79 | ADORA1 (0.44) | MEN1KMT2AADORA1ADORA2A | |
| SCHEMBL17971419 | 0.78 | ADORA2A (0.53) | GRM5MEN1KMT2AADORA1ADORA2A | |
| SCHEMBL4905628 | 0.78 | ADORA2A (0.56) | MEN1KMT2AADORA1ADORA2AALDH1A1 | |
| SCHEMBL27738558 | 0.76 | ADORA1 (0.53) | GRM5MEN1KMT2AADORA1ADORA2A | |
| SCHEMBL7220037 | 0.74 | ADORA1 (0.49) | MEN1KMT2AADORA1ADORA2AALDH1A1 | |
| SCHEMBL10205842 | 0.73 | USP7 (0.45) | MEN1KMT2AADORA1ADORA2AALDH1A1 | |
| SCHEMBL4339461 | 0.73 | ADORA1 (0.40) | MEN1KMT2AADORA1ADORA2A | |
| SCHEMBL10381958 | 0.73 | ADORA1 (0.40) | MEN1KMT2AADORA1ADORA2AMAPT | |
| SCHEMBL7219981 | 0.71 | ALDH1A1 (0.61) | GRM5MEN1KMT2AADORA1ADORA2A | |
| SCHEMBL398975 | 0.71 | ADORA1 (0.62) | GRM5ADORA1ADORA2AALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6603007-B1 | Intermediates in the fields of pharmaceuticals, agrichemicals, ligands, silver halide photosensitive materials, liquid crystals, surfactants, electrophotography and organic electroluminescence | SANKIO CHEMICAL CO., LTD. (JP) | 2003-08-05 | — | — | US | disclosed |
| EP-1231207-A1 | NOVEL BIPYRIDYL DERIVATIVES | Sankio Chemical Co., Ltd. (JP) | 2002-08-14 | — | — | EP | disclosed |