Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.55 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.55 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.55 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.55 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.52 |
| ▸ | PREP | P48147 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4905274 | 0.97 | DPP4 (0.59) | DPP4DPP7DPP8DPP9ITGB3 | |
| SCHEMBL8250574 | 0.89 | DPP4 (0.54) | DPP4DPP7DPP8DPP9PREP | |
| SCHEMBL5366307 | 0.88 | DPP4 (0.50) | DPP4DPP7DPP8DPP9PREP | |
| SCHEMBL5366301 | 0.86 | PREP (0.48) | DPP4DPP8DPP9ITGB3ITGA2B | |
| SCHEMBL6111437 | 0.86 | PREP (0.48) | DPP4DPP8DPP9ITGB3ITGA2B | |
| SCHEMBL5916433 | 0.86 | PREP (0.48) | DPP4DPP8DPP9ITGB3ITGA2B | |
| SCHEMBL13034909 | 0.86 | ITGB3 (0.47) | DPP4DPP7DPP8DPP9ITGB3 | |
| SCHEMBL13035141 | 0.84 | DPP4 (0.46) | DPP4DPP8DPP9PREP | |
| SCHEMBL3601946 | 0.84 | CTSL (0.51) | DPP4DPP8DPP9PREP | |
| SCHEMBL13444797 | 0.84 | DPP4 (0.50) | DPP4DPP8DPP9ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255126-A1 | Inhibitors of post-proline cleaving proteases | FERRING B.V. | 2008-10-16 | — | — | US | disclosed |
| US-7335677-B2 | Inhibitors of dipeptidyl peptidase IV | FERRING B.V. (NL) | 2008-02-26 | — | — | US | disclosed |
| US-7189728-B2 | Inhibitors of dipeptidyl peptidase IV | FERRING, BV (NL) | 2007-03-13 | — | — | US | disclosed |
| US-7144886-B2 | Dipeptidyl peptidase IV (DP-IV) inhibitors as anti-diabetic agents | FERRING B.V. (NL) | 2006-12-05 | — | — | US | disclosed |
| US-7125863-B2 | Inhibitors of dipeptidyl peptidase IV | FERRING BV (NL) | 2006-10-24 | — | — | US | disclosed |
| EP-1693365-A1 | Inhibitors of dipeptidyl peptidase IV | FERRING B.V. (NL) | 2006-08-23 | — | — | EP | disclosed |
| US-20050043299-A1 | Inhibitors of dipeptidyl peptidase iv | FERRING B. V. | 2005-02-24 | — | — | US | disclosed |
| US-20050004205-A1 | Novel dipeptidyl peptidase iv (dp-iv) inhibitors as anti-diabetic agents | FERRING B.V. (NL) | 2005-01-06 | — | — | US | disclosed |
| EP-1280797-B1 | INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | FERRING BV (NL) | 2004-10-13 | — | — | EP | disclosed |
| US-20040082497-A1 | Inhibitors of dipeptidyl peptidase IV | FERRING BV (NL) | 2004-04-29 | — | — | US | disclosed |
| US-20030216450-A1 | Inhibitors of dipeptidyl peptidase IV | FERRING BV (NL) | 2003-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216450-A1 | Inhibitors of dipeptidyl peptidase IV | DPP4, DPP7, DPP8 | DPP4 1/4885DPP7 2/4885DPP8 3/4885 |
| US-20040082497-A1 | Inhibitors of dipeptidyl peptidase IV | DPP4, DPP7, DPP3 | DPP4 1/4885DPP7 2/4885DPP8 6/4885 |
| US-20050004205-A1 | Novel dipeptidyl peptidase iv (dp-iv) inhibitors as anti-diabetic agents | DPP4, DPP8, DPP3 | DPP4 1/4885DPP7 4/4885DPP8 2/4885 |
| US-20050043299-A1 | Inhibitors of dipeptidyl peptidase iv | DPP4, DPP9, DPP3 | DPP4 1/4885DPP7 4/4885DPP8 9/4885 |
| US-20080255126-A1 | Inhibitors of post-proline cleaving proteases | PREP, PEPD, DPP4 | DPP4 3/4885DPP7 7/4885DPP8 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.