SCHEMBL490677

SCHEMBL490677

O=C(O)c1c[c]ccc1C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.48
ALOX15 P16050 1/20 0.48
CYP1A2 P05177 1/20 0.42
AKR1C3 P42330 2/20 0.38
CA12 O43570 3/20 0.36
CA1 P00915 3/20 0.36
CA2 P00918 3/20 0.36
CA7 P43166 3/20 0.36
CA9 Q16790 3/20 0.36
CA14 Q9ULX7 3/20 0.36
KDM4E B2RXH2 1/20 0.36
HMGB1 P09429 1/20 0.36
HPGD P15428 1/20 0.36
CA4 P22748 1/20 0.36
CA6 P23280 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
NAPRT Q6XQN6 1/20 0.36
SELL P14151 1/20 0.34
SELP P16109 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7421653 0.82 TSHR (0.40) ALDH1A1ALOX15CYP1A2CA12CA1
SCHEMBL2553639 0.81 ALDH1A1 (0.42) ALDH1A1ALOX15CYP1A2KDM4EHMGB1
SCHEMBL1406514 0.81 ALDH1A1 (0.48) ALDH1A1ALOX15CYP1A2CA12CA1
SCHEMBL3181993 0.81 ALDH1A1 (0.48) ALDH1A1ALOX15CYP1A2CA12CA1
SCHEMBL443557 0.79 ALDH1A1 (0.50) ALDH1A1ALOX15CYP1A2AKR1C3CA1
SCHEMBL6195645 0.79 MAPT (0.50) ALDH1A1ALOX15CYP1A2AKR1C3CA12
SCHEMBL232871 0.79 ALDH1A1 (0.37) ALDH1A1ALOX15CYP1A2AKR1C3CA12
SCHEMBL730792 0.79 ALB (0.41) ALDH1A1ALOX15CYP1A2CA12CA1
SCHEMBL1196449 0.79 KDM4E (0.47) ALDH1A1ALOX15CYP1A2KDM4EHPGD
SCHEMBL2550138 0.79 ALDH1A1 (0.41) ALDH1A1ALOX15CYP1A2AKR1C3KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1430 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117043230-A Polyamic acid, polyamic acid solution, polyimide substrate, laminate, and method for producing same 株式会社钟化 2023-11-10 CN claimed
CN-109071774-B Thermosetting resin composition, cured film, substrate with cured film, and electronic component 捷恩智株式会社 2021-08-03 CN claimed
US-20200347247-A1 SURFACE PRIMER COMPOSITIONS AND METHODS OF USE ENVISTA (US) 2020-11-05 US claimed
US-10696698-B2 Surface primer compositions and methods of use ORMCO CORPORATION 2020-06-30 US claimed
WO-2019188265-A1 POLYAMIC ACID, POLYAMIC ACID SOLUTION, POLYIMIDE, POLYIMIDE FILM, LAMINATE AND FLEXIBLE DEVICE, AND METHOD FOR PRODUCING POLYIMIDE FILM 株式会社カネカ 2019-10-03 WO claimed
CN-109433543-A A kind of polyimide nano coating and preparation method thereof 江苏菲沃泰纳米科技有限公司 2019-03-08 CN claimed
CN-109071774-A Thermosetting resin composition, cured film, substrate with cured film, and electronic component 捷恩智株式会社 2018-12-21 CN claimed
EP-3408272-A1 SURFACE PRIMER COMPOSITIONS AND METHODS OF USE Acatechol, Inc. (US) 2018-12-05 EP claimed
CN-108027564-A Photosensitive polyimide composition 富士胶片电子材料美国有限公司 2018-05-11 CN claimed
CN-108027563-A Photosensitive polyimide composition 富士胶片电子材料美国有限公司 2018-05-11 CN claimed
EP-0572419-B1 ANIONIC DISAZO DYES ZENECA LTD (GB) 1996-11-13 EP claimed
EP-0523240-B1 BISIMIDE COMPOUNDS, POLYIMIDE RESIN COMPOSITION PREPARED THEREFROM, AND CARBON FIBER-REINFORCED POLYIMIDE RESIN COMPOSITION MITSUI TOATSU CHEMICALS (JP) 1996-03-20 EP claimed
EP-0369733-B1 Fluorescent indicator dyes for alkali metal cations, their preparation and use UNIV CALIFORNIA (US) 1996-02-21 EP claimed
WO-1995031505-A1 DISAZO COMPOUND ZENECA LIMITED (GB) 1995-11-23 WO claimed
EP-0368590-B1 Production process for polyimide fibers MITSUI TOATSU CHEMICALS (JP) 1995-01-25 EP claimed
US-5281263-A Disazo dyes for inks printed paper IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1994-01-25 US claimed
EP-0572419-A1 ANIONIC DISAZO DYES. ZENECA LTD (GB) 1993-12-08 EP claimed
WO-1992013037-A1 ANIONIC DISAZO DYES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-08-06 WO claimed
EP-0031708-B1 CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATES THEREFOR ICI PHARMA (FR) 1984-06-13 EP claimed
EP-0031708-A2 Cephalosporin derivatives, processes for their manufacture, pharmaceutical compositions containing them and intermediates therefor ICI PHARMA (FR) 1981-07-08 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10696698-B2 Surface primer compositions and methods of use SP1, GPER1, GRIN1 ALDH1A1 1177/4885ALOX15 3081/4885CYP1A2 2409/4885
US-20200347247-A1 SURFACE PRIMER COMPOSITIONS AND METHODS OF USE SP1, GPER1, GRIN1 ALDH1A1 1177/4885ALOX15 3081/4885CYP1A2 2409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.