Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL750508 | 0.83 | ALDH1A1 (0.50) | ALDH1A1TP53TSHRSMN1; SMN2CASP1 | |
| SCHEMBL443893 | 0.81 | CES2 (0.35) | ALDH1A1TP53SMN1; SMN2POLBLMNA | |
| SCHEMBL4806709 | 0.81 | KMT2A (0.41) | ALDH1A1TSHRKDM4EMAPTPOLB | |
| SCHEMBL490677 | 0.79 | ALDH1A1 (0.48) | ALDH1A1TP53TSHRSMN1; SMN2KDM4E | |
| SCHEMBL4323616 | 0.76 | ALDH1A1 (0.50) | ALDH1A1TP53TSHRSMN1; SMN2KDM4E | |
| SCHEMBL5465624 | 0.76 | ABL1 (0.42) | ALDH1A1TSHRSMN1; SMN2KDM4EMAPT | |
| SCHEMBL18547962 | 0.76 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2CASP1KDM4EMAPT | |
| SCHEMBL3181993 | 0.76 | ALDH1A1 (0.48) | ALDH1A1TSHRSMN1; SMN2CASP1KDM4E | |
| SCHEMBL2553639 | 0.76 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2KDM4EPOLBALOX15 | |
| SCHEMBL730792 | 0.74 | ALB (0.41) | ALDH1A1SMN1; SMN2KDM4ELMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11160278-B2 | Use of active substances for controlling virus infection in plants | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2021-11-02 | — | — | US | claimed |
| CN-108463108-B | Use of active substances for controlling plant virus infections | 拜耳作物科学股份公司 | 2021-02-19 | — | — | CN | claimed |
| EP-3402334-B1 | USE OF ACTIVE SUBSTANCES FOR CONTROLLING VIRUS INFECTION IN PLANTS | BAYER CROPSCIENCE AG (DE) | 2020-05-27 | — | — | EP | claimed |
| CN-106038558-B | Compounds and methods for modulating integrin CD11b/CD18 | GB006公司 | 2020-01-10 | — | — | CN | claimed |
| US-20190335752-A1 | USE OF ACTIVE SUBSTANCES FOR CONTROLLING VIRUS INFECTION IN PLANTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-11-07 | — | — | US | claimed |
| EP-3402334-A1 | USE OF ACTIVE SUBSTANCES FOR CONTROLLING VIRUS INFECTION IN PLANTS | Bayer CropScience Aktiengesellschaft (DE) | 2018-11-21 | — | — | EP | claimed |
| CN-108463108-A | Active material is used to prevent the purposes of plant virus infection | 拜耳作物科学股份公司 | 2018-08-28 | — | — | CN | claimed |
| WO-2017121811-A1 | USE OF ACTIVE SUBSTANCES FOR CONTROLLING VIRUS INFECTION IN PLANTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-07-20 | — | — | WO | claimed |
| US-9682940-B2 | Indazole derivatives useful as CB-1 inverse agonists | JANSSEN PHARMACEUTICA NV (BE) | 2017-06-20 | — | — | US | claimed |
| WO-2017034872-A1 | INDAZOLE DERIVATIVES USEFUL AS CB-1 INVERSE AGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2017-03-02 | — | — | WO | claimed |
| US-20170057925-A1 | INDAZOLE DERIVATIVES USEFUL AS CB-1 INVERSE AGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2017-03-02 | — | — | US | claimed |
| CN-106038558-A | Compounds and methods for regulating integrin CD11B/CD18 | 阿德黑雷制药公司 | 2016-10-26 | — | — | CN | claimed |
| CN-103189500-B | Compounds and methods for modulating integrin CD11b/CD18 | 阿德黑雷制药公司 | 2016-06-15 | — | — | CN | claimed |
| US-9023876-B2 | Compounds and methods for regulating integrins | ADHAERE PHARMACEUTICALS, INC. (US) | 2015-05-05 | — | — | US | claimed |
| US-20070276011-A1 | Plasminogen Activator Inhibitor-1 Inhibitor | INSTITUTE OF MEDICINAL MOLECULAR DESIGN. INC. (JP) | 2007-11-29 | — | — | US | claimed |
| EP-1666469-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITOR | Institute of Medicinal Molecular Design, Inc. (JP) | 2006-06-07 | — | — | EP | claimed |
| CN-1753871-A | Water compatible sterically hindered alkoxyamines and hydroxy substituted alkoxyamines | CIBA SC HOLDING AG (CH) | 2006-03-29 | — | — | CN | claimed |
| CN-111433290-B | Azo compound or salt thereof, and polarizing element, polarizing plate and display device each comprising the same | 日本化药株式会社 | 2022-06-14 | — | — | CN | disclosed |
| US-4935466-A | Modified block copolymers and process for the preparation thereof | SHELL OIL COMPANY (US) | 1990-06-19 | — | — | US | disclosed |
| EP-0368395-A1 | Lubricating oil composition | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-05-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11160278-B2 | Use of active substances for controlling virus infection in plants | GUSB, AS3MT, CAT | ALDH1A1 1765/4885TP53 2216/4885TSHR 4513/4885 |
| US-20070276011-A1 | Plasminogen Activator Inhibitor-1 Inhibitor | SERPINE1, SERPINC1, SERPINB1 | ALDH1A1 1861/4885TP53 3114/4885TSHR 2228/4885 |
| US-20190335752-A1 | USE OF ACTIVE SUBSTANCES FOR CONTROLLING VIRUS INFECTION IN PLANTS | GUSB, AS3MT, CAT | ALDH1A1 1765/4885TP53 2216/4885TSHR 4513/4885 |
| US-20170057925-A1 | INDAZOLE DERIVATIVES USEFUL AS CB-1 INVERSE AGONISTS | CNR1, GPR119, CNR2 | ALDH1A1 689/4885TP53 4463/4885TSHR 703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.