SCHEMBL4907122

SCHEMBL4907122

Nc1nc(N)c2nc(O)[nH]c2n1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CG P48736 5/20 0.33
DHFR P00374 1/20 0.33
ADORA2A P29274 1/20 0.33
MAPT P10636 1/20 0.31
PIK3CD O00329 1/20 0.30
PIK3C2B O00750 1/20 0.30
PDXK O00764 1/20 0.30
GAK O14976 1/20 0.30
MAP3K7 O43318 1/20 0.30
RIPK2 O43353 1/20 0.30
PIP5K1C O60331 1/20 0.30
STK16 O75716 1/20 0.30
PIK3C2G O75747 1/20 0.30
PRKD3 O94806 1/20 0.30
OXSR1 O95747 1/20 0.30
LATS1 O95835 1/20 0.30
ABL1 P00519 1/20 0.30
EGFR P00533 1/20 0.30
ERBB2 P04626 1/20 0.30
LCK P06239 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30819131 1.00 PIK3CG (0.33) PIK3CGDHFRADORA2AMAPTPIK3CD
Water SCHEMBL8757459 0.98 DHFR (0.33) PIK3CGDHFRADORA2AMAPT
SCHEMBL7168821 0.83 MAPT (0.31) MAPT
SCHEMBL524228 0.83
SCHEMBL13522498 0.79 ADORA1 (0.30) ADORA2A
SCHEMBL19192257 0.79
SCHEMBL4002943 0.77 CSNK2A2 (0.35) DHFRADORA2AMAPTCSNK2A2CSNK2A1
SCHEMBL5133268 0.74 CSNK2A2 (0.35) DHFRADORA2AMAPTCSNK2A2CSNK2A1
SCHEMBL16513155 0.74 ADORA2A (0.33) DHFRADORA2AMAPT
SCHEMBL1766002 0.74 ADORA2A (0.33) ADORA2AMAPTEGFRFLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9255182-B2 Data storage medium and method for high density data storage INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2016-02-09 US claimed
US-20080175135-A1 DATA STORAGE MEDIUM AND METHOD FOR HIGH DENSITY DATA STORAGE DUERIG URS T 2008-07-24 US claimed
US-20080076903-A1 DATA STORAGE MEDIUM AND METHOD FOR HIGH DENSITY DATA STORAGE INTERNATIONAL BUSINESS MACHINES CORPORATION 2008-03-27 US claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
EP-0673783-B1 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORP (US) 2000-07-05 EP claimed
US-5457486-A Thermal printing XEROX CORPORATION (US) 1995-10-10 US claimed
CN-117777474-A Sustained-release polycarboxylate water reducer modified graphene oxide, and preparation method and application thereof 北京建筑材料科学研究总院有限公司 2024-03-29 CN disclosed
CN-117658515-A Branched-structure graphene oxide-polycarboxylate water reducer composite material and preparation method thereof 北京工业大学 2024-03-08 CN disclosed
US-9255182-B2 Data storage medium and method for high density data storage INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2016-02-09 US disclosed
US-7642350-B2 Purine derivatives PFIZER LIMITED (GB) 2010-01-05 US disclosed
US-7642350-B2 Purine derivatives PFIZER LIMITED (GB) 2010-01-05 US disclosed
US-20080175135-A1 DATA STORAGE MEDIUM AND METHOD FOR HIGH DENSITY DATA STORAGE DUERIG URS T 2008-07-24 US disclosed
US-5582858-A Adhesive layer in multi-level packaging and organic material as a metal diffusion barrier INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1996-12-10 US disclosed
US-5569739-A Adhesive layer in multi-level packaging and organic material as a metal diffusion barrier INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1996-10-29 US disclosed
US-5326643-A Adhesive layer in multi-level packaging and organic material as a metal diffusion barrier INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1994-07-05 US disclosed
EP-0536606-A2 An adhesive layer in multilevel packaging and organic material as a metal diffusion barrier INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1993-04-14 EP disclosed
EP-0034038-B1 USE OF SILVER HALIDE DEVELOPMENT ACCELERATORS, PHOTOGRAPHIC FILMS AND PROCESSES FOR DEVELOPING LITHOGRAFIC FILM E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-05-30 EP disclosed
US-4292391-A PYRAZOLO/3,4-D/PYRIMIDINES; PHOTOLITHOGRAPHY E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-09-29 US disclosed
EP-0034038-A1 Use of silver halide development accelerators, photographic films and processes for developing lithografic film E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-08-19 EP disclosed