⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30819131 | 0.83 | PIK3CG (0.33) | — | |
| SCHEMBL4907122 | 0.83 | PIK3CG (0.33) | — | |
| Water SCHEMBL8757459 | 0.81 | DHFR (0.33) | — | |
| SCHEMBL13522498 | 0.79 | ADORA1 (0.30) | — | |
| SCHEMBL19192257 | 0.79 | — | — | |
| SCHEMBL42336 | 0.72 | PIK3CG (0.42) | — | |
| SCHEMBL9172220 | 0.71 | PARP1 (0.49) | — | |
| SCHEMBL7168821 | 0.70 | MAPT (0.31) | — | |
| SCHEMBL13982477 | 0.68 | — | — | |
| Isoguanine SCHEMBL887740 | 0.67 | PARP1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 865 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4681774-A2 | KHK INHIBITORS | Gilead Sciences, Inc. (US) | 2026-01-21 | — | — | EP | claimed |
| EP-4313967-B1 | KHK INHIBITORS | GILEAD SCIENCES INC (US) | 2025-11-12 | — | — | EP | claimed |
| EP-4313967-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2024-02-07 | — | — | EP | claimed |
| US-20230416361-A1 | ENGINEERED CD200R ANTIBODIES AND USES THEREOF | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2023-12-28 | — | — | US | claimed |
| CN-117120429-A | KHK inhibitor | 吉利德科学公司 | 2023-11-24 | — | — | CN | claimed |
| WO-2023196866-A1 | ENGINEERED CD200R ANTIBODIES AND USES THEREOF | MIROBIO LIMITED (GB) | 2023-10-12 | — | — | WO | claimed |
| US-20230079863-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. | 2023-03-16 | — | — | US | claimed |
| WO-2022212194-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2022-10-06 | — | — | WO | claimed |
| EP-3519558-A1 | USE OF ENGINEERED RENAL TISSUES IN ASSAYS | Organovo, Inc. (US) | 2019-08-07 | — | — | EP | claimed |
| WO-2018064323-A1 | USE OF ENGINEERED RENAL TISSUES IN ASSAYS | ORGANOVO, INC. (US) | 2018-04-05 | — | — | WO | claimed |
| WO-2009127230-A1 | MODIFIED (m)RNA FOR SUPPRESSING OR AVOIDING AN IMMUNOSTIMULATORY RESPONSE AND IMMUNOSUPPRESSIVE COMPOSITION | CUREVAC GMBH (DE) | 2009-10-22 | — | — | WO | claimed |
| JP-3065650-A | — | — | None | — | — | JP | disclosed |
| US-12622876-B2 | Methods of suppressing delivery of exosomes to liver and spleen | LONZA SALES AG (CH) | 2026-05-12 | — | — | US | disclosed |
| US-20260092053-A1 | KHK INHIBITORS | GILEAD SCIENCES INC (US) | 2026-04-02 | — | — | US | disclosed |
| EP-4705318-A2 | KIDNEY-TARGETING AAV CAPSIDS AND METHODS OF USE THEREOF | Oregon Health & Science University (US) | 2026-03-11 | — | — | EP | disclosed |
| EP-0034038-B1 | USE OF SILVER HALIDE DEVELOPMENT ACCELERATORS, PHOTOGRAPHIC FILMS AND PROCESSES FOR DEVELOPING LITHOGRAFIC FILM | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-05-30 | — | — | EP | disclosed |
| US-4292391-A | PYRAZOLO/3,4-D/PYRIMIDINES; PHOTOLITHOGRAPHY | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-09-29 | — | — | US | disclosed |
| EP-0034038-A1 | Use of silver halide development accelerators, photographic films and processes for developing lithografic film | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-08-19 | — | — | EP | disclosed |
| US-4112070-A | Blood preservation system | RESEARCH CORPORATION (US) | 1978-09-05 | — | — | US | disclosed |
| JP-H00365650-A | — | — | 0001-01-01 | — | — | JP | disclosed |