Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 2/20 | 1.00 |
| ▸ | PPARG | P37231 | 2/20 | 0.60 |
| ▸ | PPARA | Q07869 | 1/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2571084 | 0.91 | LDHA (0.83) | LDHAPPARGPPARASLC6A4CYP1A2 | |
| SCHEMBL27454162 | 0.88 | LDHA (0.77) | LDHAPPARGPPARASLC6A4CYP1A2 | |
| SCHEMBL6378617 | 0.87 | LDHA (0.76) | LDHAPPARGPPARAFFAR1 | |
| SCHEMBL10436394 | 0.86 | LDHA (0.76) | LDHAPPARGPPARASLC6A4CYP1A2 | |
| SCHEMBL6688761 | 0.86 | LDHA (0.76) | LDHAPPARGPPARASLC6A4CYP1A2 | |
| SCHEMBL7353111 | 0.86 | LDHA (0.75) | LDHAPPARGPPARASLC6A4FFAR1 | |
| SCHEMBL9411838 | 0.86 | LDHA (0.75) | LDHAPPARGPPARASLC6A4FFAR1 | |
| SCHEMBL6381907 | 0.86 | LDHA (0.73) | LDHAPPARGPPARAFFAR1 | |
| SCHEMBL9463780 | 0.85 | LDHA (0.73) | LDHAPPARGPPARASLC6A4 | |
| SCHEMBL8039405 | 0.85 | LDHA (0.73) | LDHAPPARGPPARASLC6A4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023221665-A1 | DIPHENOLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 帕潘纳(北京)科技有限公司 | 2023-11-23 | — | — | WO | disclosed |
| CN-108033916-B | Preparation of amino acid ester compound and application of amino acid ester compound in preventing and treating tobacco diseases | 贵州理工学院 | 2021-02-26 | — | — | CN | disclosed |
| CN-105209453-B | The quinolyl conditioning agent of the methylene connection of ROR γ T | 詹森药业有限公司 | 2017-06-20 | — | — | CN | disclosed |
| EP-2909192-B1 | METHYLENE LINKED QUINOLINYL MODULATORS OF ROR-GAMMA-T | JANSSEN PHARMACEUTICA NV (BE) | 2017-05-17 | — | — | EP | disclosed |
| US-9290476-B2 | Methylene linked quinolinyl modulators of RORγt | JANSSEN PHARMACEUTICA NV (BE) | 2016-03-22 | — | — | US | disclosed |
| US-9290476-B2 | Methylene linked quinolinyl modulators of RORγt | JANSSEN PHARMACEUTICA NV (BE) | 2016-03-22 | — | — | US | disclosed |
| US-9290476-B2 | Methylene linked quinolinyl modulators of RORγt | JANSSEN PHARMACEUTICA NV (BE) | 2016-03-22 | — | — | US | disclosed |
| CN-105209453-A | Methylene linked quinolinyl modulators of ROR-gamma-T | JANSSEN PHARMACEUTICA NV | 2015-12-30 | — | — | CN | disclosed |
| EP-2909192-A1 | METHYLENE LINKED QUINOLINYL MODULATORS OF ROR-GAMMA-T | Janssen Pharmaceutica, N.V. (BE) | 2015-08-26 | — | — | EP | disclosed |
| EP-2172450-B9 | NOVEL MALONIC ACID SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | MITSUBISHI TANABE PHARMA CORP (JP) | 2014-10-08 | — | — | EP | disclosed |
| WO-1995009620-A1 | SULFOXIMINE AND SULFODIIMINE MATRIX METALLOPROTEINASE INHIBITORS | FLORIDA STATE UNIVERSITY (US) | 1995-04-13 | — | — | WO | disclosed |
| US-4863922-A | Substituted aromatic sulfonamides as antiglaucoma agents, compositions and use | MERCK & CO., INC. (US) | 1989-09-05 | — | — | US | disclosed |
| US-4824968-A | REMOVING HYDROXYL GROUP WITH SODIUM IODIDE AND DICHLORODIMETHYLSILANE IN ACETONITRILE | MERCK & CO., INC. (US) | 1989-04-25 | — | — | US | disclosed |
| US-4820848-A | Substituted aromatic sulfonamides as antiglaucoma agents | MERCK & CO., INC. (US) | 1989-04-11 | — | — | US | disclosed |
| US-4797413-A | Thieno thiopyran sulfonamide derivatives, pharmaceutical compositions and use | MERCK & CO., INC. (US) | 1989-01-10 | — | — | US | disclosed |
| EP-0296879-A1 | Substituted aromatic sulfonamides as antiglaucoma agents | MERCK & CO. INC. (US) | 1988-12-28 | — | — | EP | disclosed |
| EP-0120304-A2 | Substituted 4,10-dihydro-10-oxothieno benzoxepins and intermediates thereof, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1984-10-03 | — | — | EP | disclosed |
| EP-0066956-B1 | ENKEPHALINASE ENZYME INHIBITING COMPOUNDS | PFIZER INC. (US) | 1984-08-08 | — | — | EP | disclosed |
| EP-0066956-A1 | Enkephalinase enzyme inhibiting compounds | PFIZER INC. (US) | 1982-12-15 | — | — | EP | disclosed |
| US-4329495-A | USEFUL AS ANALGESICS OR ANTICONVULSANTS, CHIRAL 2-(2-BENZYL-3-MERCAPTOPROPIONYLAMINO)-THIOBUTYRIC ACIDS, OR ALKANOL DERIVATIVES | PFIZER INC. (US) | 1982-05-11 | — | — | US | disclosed |