SCHEMBL4907175

SCHEMBL4907175

C=CC(=O)OC(CO)OC(=O)C=C

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.44
ALDH1A1 P00352 4/20 0.40
TP53 P04637 3/20 0.40
HIF1A Q16665 3/20 0.40
CYP3A4 P08684 2/20 0.40
MAPK1 P28482 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
HSD17B10 Q99714 1/20 0.39
HPGD P15428 1/20 0.35
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9318539 0.83 TSHR (0.50) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL8988187 0.83 TSHR (0.38) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL2851825 0.81 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL116157 0.80 TSHR (0.44) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL5966667 0.80 TSHR (0.41) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL4444011 0.80 TSHR (0.41) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL23668048 0.78 TSHR (0.40) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL4197867 0.78
SCHEMBL1138627 0.78 TSHR (0.45) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL30661313 0.78 TSHR (0.40) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0956153-B1 DISPERSING AGENT EFKA ADDITIVES B V (NL) 2002-10-02 EP claimed
EP-0956153-A1 DISPERSING AGENT Ekfa Chemicals B.V. (NL) 1999-11-17 EP claimed
US-5882393-A REACTION PRODUCT OF POLYISOCYANATES WITH A COMPOUND OF RING STRUCTURE WITH AT LEAST ONE NITROGEN ATOM IN RING; LACQUER EFKA CHEMICALS B.V. (NL) 1999-03-16 US claimed
WO-1997026984-A1 DISPERSING AGENT EKFA CHEMICALS B.V. (NL) 1997-07-31 WO claimed
US-7338737-B2 Photosensitive resin composition, thin film panel made with photosensitive resin composition, and method for manufacturing thin film panel SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-03-04 US disclosed
US-7297452-B2 Alkali-soluble resin; a quinone diazide; and a mixture of surfactants including a 3-(perfluoroalkyl)-1,2-epoxypropane, reaction product between methylhydrobis(trimethylsiloxy)silane and polyalkylene glycol monoallyl ether preferably having a molecular weight from 200 to 500 and a 2nd ether silicone SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-11-20 US disclosed
US-20070254221-A1 Akali-soluble resin, quinone diazide, surfactant mixture of a 3-perfluoroalkylpropane epoxide and polyethersilicones), and a solvent; high-quality display panels with uniformly-coated insulating layers. SAMSUNG DISPLAY CO., LTD. (KR) 2007-11-01 US disclosed
US-20060141393-A1 Alkali-soluble resin; a quinone diazide; and a mixture of surfactants including a 3-(perfluoroalkyl)-1,2-epoxypropane, reaction product between methylhydrobis(trimethylsiloxy)silane and polyalkylene glycol monoallyl ether preferably having a molecular weight from 200 to 500 and a 2nd ether silicone SAMSUNG ELECTRONICS CO., LTD. 2006-06-29 US disclosed
US-20060131267-A1 Photosensitive resin composition, thin film panel made with photosensitive resin composition, and method for manufacturing thin film panel SAMSUNG DISPLAY CO., LTD. (KR) 2006-06-22 US disclosed
US-5547762-A THERMOSETTING RESIN LAYER BRIDGESTONE CORPORATION (JP) 1996-08-20 US disclosed