Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28385985 | 0.88 | TSHR (0.41) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL27984153 | 0.86 | TSHR (0.48) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL13569464 | 0.85 | TSHR (0.38) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL4907175 | 0.81 | TSHR (0.44) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL27854078 | 0.80 | TSHR (0.45) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL544590 | 0.80 | TSHR (0.45) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL3278404 | 0.80 | ALDH1A1 (0.41) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL7766220 | 0.80 | ALDH1A1 (0.41) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL2119381 | 0.80 | TSHR (0.45) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL5369953 | 0.79 | TSHR (0.50) | TSHRALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100129777-A1 | KIT FOR FIXING A DENTAL RESTORATION MATERIAL ON A TOOTH SUBSTANCE | ERNST MÜHLBAUER GMBH & CO. KG (DE) | 2010-05-27 | — | — | US | disclosed |