SCHEMBL4907247

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4910659	0.89	CCR2 (1.00)	CCR2CCR1CYP1A2CYP3A4CYP2D6
	SCHEMBL4912539	0.87	CCR2 (0.83)	CCR2CCR1CYP1A2CYP3A4CYP2D6
	SCHEMBL4902621	0.83	CCR2 (0.67)	CCR2CCR1CYP1A2CYP3A4CYP2D6
	SCHEMBL5666655	0.80	CCR2 (0.83)	CCR2CCR1CYP1A2CYP3A4CYP2D6
	SCHEMBL12200779	0.78	CCR2 (0.73)	CCR2CCR1ALDH1A1KMT2APOLB
	SCHEMBL4908265	0.78	CCR2 (1.00)	CCR2CYP1A2CYP3A4CYP2D6CYP2C9
	SCHEMBL4903026	0.77	CCR2 (0.67)	CCR2CCR1CYP1A2CYP3A4CYP2D6
	SCHEMBL492321	0.76	TSHR (0.68)	CCR2CCR1ALDH1A1KMT2AKDM4E
	SCHEMBL3113839	0.76	KMT2A (0.77)	ALDH1A1KMT2APOLBL3MBTL1KDM4E
	SCHEMBL4913269	0.76	CCR2 (0.82)	CCR2CYP1A2CYP3A4CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.