SCHEMBL490743

SCHEMBL490743

Brc1cccc2c(-c3ccccc3)c3ccccc3c(-c3ccccc3)c12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.43
MAPT P10636 3/20 0.43
KDM4E B2RXH2 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
CYP1A2 P05177 2/20 0.42
CYP3A4 P08684 2/20 0.42
CYP2C9 P11712 2/20 0.42
CYP2C19 P33261 2/20 0.42
ALDH1A1 P00352 3/20 0.41
ACHE P22303 2/20 0.39
FABP4 P15090 1/20 0.37
ESR1 P03372 3/20 0.35
ESR2 Q92731 3/20 0.35
LMNA P02545 2/20 0.35
POLB P06746 1/20 0.35
HPGD P15428 1/20 0.35
TSHR P16473 1/20 0.35
HSD17B10 Q99714 1/20 0.35
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Alcohol SCHEMBL27941657 0.94 ACHE (0.40) MAPK1MAPTKDM4ETDP1L3MBTL1
SCHEMBL28763203 0.94 MAPK1 (0.42) MAPK1MAPTKDM4ETDP1L3MBTL1
SCHEMBL13299977 0.86 MAPK1 (0.40) MAPK1MAPTKDM4ETDP1L3MBTL1
SCHEMBL27989595 0.80 MAPK1 (0.41) MAPK1MAPTKDM4ETDP1L3MBTL1
SCHEMBL7270754 0.79 ACHE (0.50) MAPK1MAPTKDM4ETDP1L3MBTL1
SCHEMBL5599120 0.78 ACHE (0.42) MAPK1MAPTKDM4ETDP1L3MBTL1
SCHEMBL27947410 0.78 SIRT2 (0.40) KDM4ECYP1A2ALDH1A1ACHEESR1
SCHEMBL5880687 0.77 NQO2 (0.45) MAPK1MAPTKDM4ETDP1L3MBTL1
SCHEMBL27872521 0.77 ESR1 (0.50) MAPK1MAPTKDM4ETDP1L3MBTL1
SCHEMBL3437832 0.77 ALDH1A1 (0.41) MAPK1MAPTKDM4ETDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110446976-A Photosensitive resin composition ASAHI CHEMICAL IND 2019-11-12 CN disclosed
US-10079345-B2 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-09-18 US disclosed
CN-104425738-B Organic light emitting apparatus 三星显示有限公司 2018-04-03 CN disclosed
CN-104350030-B Gas generating material and micropump 积水化学工业株式会社 2017-09-15 CN disclosed
US-20160197278-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device Using Anthracene Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-07-07 US disclosed
US-20160197278-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device Using Anthracene Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-07-07 US disclosed
US-20160197278-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device Using Anthracene Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-07-07 US disclosed
CN-103258963-B Light-emitting component, light-emitting device and electronic equipment SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-05-25 CN disclosed
US-9287511-B2 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-03-15 US disclosed
US-9287511-B2 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-03-15 US disclosed
US-7842945-B2 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-11-30 US disclosed
CN-1949557-B Organic electroluminescence device LG ELECTRONICS INC 2010-09-29 CN disclosed
EP-2084123-A1 ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-08-05 EP disclosed
CN-101432259-A Anthracene derivative, and light-emitting element, light-emitting device, and electronic device using anthracene derivative SEMICONDUCTOR ENERGY LAB (JP) 2009-05-13 CN disclosed
US-20080017853-A1 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-01-24 US disclosed
US-20080017853-A1 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-01-24 US disclosed
US-20080017853-A1 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-01-24 US disclosed
WO-2007125934-A1 ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-11-08 WO disclosed
WO-2007125934-A1 ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-11-08 WO disclosed
CN-1949557-A Organic electroluminescence device LG ELECTRONICS INC (KR) 2007-04-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10079345-B2 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative XPOT, XPO1, XPO7 MAPK1 1595/4885MAPT 3663/4885KDM4E 3837/4885
US-20080017853-A1 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative XPOT, XPO1, XPO7 MAPK1 1595/4885MAPT 3663/4885KDM4E 3837/4885
US-20160197278-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device Using Anthracene Derivative XPOT, XPO1, XPO7 MAPK1 1595/4885MAPT 3663/4885KDM4E 3837/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.