Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CPA1 | P15085 | 2/20 | 0.36 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.36 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.36 |
| ▸ | CPB1 | P15086 | 1/20 | 0.36 |
| ▸ | CPA3 | P15088 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11137284 | 0.85 | L3MBTL1 (0.71) | L3MBTL1ALDH1A1GAAPOLBTDP1 | |
| SCHEMBL11136320 | 0.82 | CYP2C19 (0.40) | L3MBTL1ALDH1A1GAAPOLBTDP1 | |
| SCHEMBL29903902 | 0.81 | L3MBTL1 (0.61) | L3MBTL1ALDH1A1GAAPOLBTDP1 | |
| SCHEMBL146867 | 0.81 | L3MBTL1 (0.61) | L3MBTL1ALDH1A1GAAPOLBTDP1 | |
| SCHEMBL377175 | 0.81 | L3MBTL1 (0.61) | L3MBTL1ALDH1A1GAAPOLBTDP1 | |
| SCHEMBL377609 | 0.81 | L3MBTL1 (0.61) | L3MBTL1ALDH1A1GAAPOLBTDP1 | |
| SCHEMBL647490 | 0.80 | AKR1C3 (0.46) | L3MBTL1ALDH1A1GAAPOLBCYP2C19 | |
| SCHEMBL23782080 | 0.79 | L3MBTL1 (0.59) | L3MBTL1ALDH1A1GAAPOLBTDP1 | |
| SCHEMBL6739142 | 0.79 | L3MBTL1 (0.59) | L3MBTL1ALDH1A1GAAPOLBTDP1 | |
| SCHEMBL27939444 | 0.79 | L3MBTL1 (0.65) | L3MBTL1ALDH1A1GAAPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8105770-B2 | Method of detecting amplification or deletion in genomic DNA Fragment | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2012-01-31 | — | — | US | disclosed |
| US-20100129293-A1 | Near Infrared Imaging Agent | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT BERLIN (DE) | 2010-05-27 | — | — | US | disclosed |
| US-20100112711-A1 | METHOD OF DETECTING AMPLIFICATION OR DELETION IN GENOMIC DNA FRAGMENT | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2010-05-06 | — | — | US | disclosed |
| US-7655217-B2 | Near infrared imaging agent | Institut fur Diagnosikforschung GmbH (DE) | 2010-02-02 | — | — | US | disclosed |
| EP-2119797-A1 | METHOD OF DETECTING AMPLIFICATION OR DELETION IN GENOMIC DNA FRAGMENT | Wako Pure Chemical Industries, Ltd. (JP) | 2009-11-18 | — | — | EP | disclosed |
| US-7445767-B2 | In-vivo diagnostic method by near infrared radiation | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT BERLIN (DE) | 2008-11-04 | — | — | US | disclosed |
| US-20060165599-A1 | Near infrared imaging agent | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH (DE) | 2006-07-27 | — | — | US | disclosed |
| US-20060165598-A1 | In-vivo diagnostic method by near infrared radiation | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT BERLIN (DE) | 2006-07-27 | — | — | US | disclosed |
| US-7025949-B2 | In-vivo diagnostic method by means of near infrared radiation | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT BERLIN (DE) | 2006-04-11 | — | — | US | disclosed |
| US-6926885-B2 | In-vivo diagnostic method by means of near infrared radiation | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH (DE) | 2005-08-09 | — | — | US | disclosed |
| US-20050169844-A1 | Near infrared imaging agent | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT BERLIN (DE) | 2005-08-04 | — | — | US | disclosed |
| US-6913743-B2 | As contrast medium for fluorescence and transillumination diagnostics; drugs | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT BERLIN (DE) | 2005-07-05 | — | — | US | disclosed |
| US-20050106106-A1 | In-vivo diagnostic method by near infrared radiation | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT BERLIN (DE) | 2005-05-19 | — | — | US | disclosed |
| US-20030170179-A1 | Near infrared imaging agent | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITA (COPY) | 2003-09-11 | — | — | US | disclosed |
| US-20030026763-A1 | In-vivo diagnostic method by means of near infrared radiation | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT BERLIN | 2003-02-06 | — | — | US | disclosed |
| CN-1089008-C | In-vivo diagnostic process by near infrared radiation | DIAGNOSTIKFORSCHUNG INST (DE) | 2002-08-14 | — | — | CN | disclosed |
| US-20010055567-A1 | In-vivo diagnostic method by means of near infrared radiation | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT BERLIN | 2001-12-27 | — | — | US | disclosed |
| US-6258340-B1 | USING WATER-SOLUBLE DYES AND THEIR BIOMOLECULE ADDUCTS EACH HAVING SPECIFIC PHOTOPHYSICAL AND PHARMOCHEMICAL PROPERTIES | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH (DE) | 2001-07-10 | — | — | US | disclosed |
| US-6083485-A | USEING WATER-SOLUBLE DYES AND THEIR BIOMOLECULE ADDUCTS AS CONTRAST MEDIUM FOR FLUORESCENCE AND TRANSILLUMINATION DIAGNOSTICS IN THE NEAR INFRARED RADIATION RANGE | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH (DE) | 2000-07-04 | — | — | US | disclosed |
| CN-1174511-A | In-vivo diagnostic process by near infrared radiation | DIAGNOSTIKFORSCHUNG INST (DE) | 1998-02-25 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060165598-A1 | In-vivo diagnostic method by near infrared radiation | GUSB, CYBA, ABCG2 | L3MBTL1 2727/4885ALDH1A1 127/4885GAA 1632/4885 |
| US-20100112711-A1 | METHOD OF DETECTING AMPLIFICATION OR DELETION IN GENOMIC DNA FRAGMENT | GLB1, GDA, DNTT | L3MBTL1 509/4885ALDH1A1 1642/4885GAA 130/4885 |
| US-20100129293-A1 | Near Infrared Imaging Agent | UGT1A10, ABCG2, SLCO1B1 | L3MBTL1 3050/4885ALDH1A1 152/4885GAA 1404/4885 |
| US-20050106106-A1 | In-vivo diagnostic method by near infrared radiation | GUSB, CYBA, ABCG2 | L3MBTL1 2727/4885ALDH1A1 127/4885GAA 1632/4885 |
| US-20050169844-A1 | Near infrared imaging agent | UGT1A10, ABCG2, SLCO1B1 | L3MBTL1 3050/4885ALDH1A1 152/4885GAA 1404/4885 |
| US-20060165599-A1 | Near infrared imaging agent | UGT1A10, ABCG2, SLCO1B1 | L3MBTL1 3050/4885ALDH1A1 152/4885GAA 1404/4885 |
| US-20010055567-A1 | In-vivo diagnostic method by means of near infrared radiation | GUSB, ABCG2, SLCO1B1 | L3MBTL1 3000/4885ALDH1A1 153/4885GAA 1100/4885 |
| US-20030026763-A1 | In-vivo diagnostic method by means of near infrared radiation | GUSB, ABCG2, SLCO1B1 | L3MBTL1 3000/4885ALDH1A1 153/4885GAA 1100/4885 |
| US-20030170179-A1 | Near infrared imaging agent | UGT1A10, ABCG2, SLCO1B1 | L3MBTL1 3050/4885ALDH1A1 152/4885GAA 1404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.